Bioidentical Hormones - U.S. Senate Special Committee on Aging
Bioidentical Hormones - U.S. Senate Special Committee on Aging Bioidentical Hormones - U.S. Senate Special Committee on Aging
Post-WHI: Additional Issues Are hormone effects different if started immediately after menopause? - Secondary analyses of combined WHI Trials * Women starting hormones close to the menopause may have fewer heart attacks and deaths compared to the increases in women distant from the menopause * Stroke and breast cancer increased irrespective of years since menopause * Provides some reassurance that younger women using hormones for the short term for relief of hot flashes and night sweats are not at increased risk of heart disease * Older women with hot flashes and night sweats are at high risk if they start hormone therapy - Ongoing surrogate outcome trials (imaging studies of coronary and brain arteries) in younger women - Findings should not be taken to imply that any early benefit for coronary disease will persist into older ages * Would estradiol have had a different effect? * Role of route of administration (ltransdermal versus oral)
Statement of the American Pharmacists Association 230 On
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Statement<br />
of the<br />
American<br />
Pharmacists<br />
Associati<strong>on</strong><br />
230<br />
On <str<strong>on</strong>g>Bioidentical</str<strong>on</strong>g> <str<strong>on</strong>g>Horm<strong>on</strong>es</str<strong>on</strong>g>:<br />
Sound Science or Bad Medicine?<br />
Before the <str<strong>on</strong>g>Special</str<strong>on</strong>g> <str<strong>on</strong>g>Committee</str<strong>on</strong>g> <strong>on</strong> <strong>Aging</strong><br />
United States <str<strong>on</strong>g>Senate</str<strong>on</strong>g><br />
April 19, 2007<br />
American Pharmnacists.Associati<strong>on</strong><br />
1100 1 5 th St NW<br />
,4oJ . Suite 400<br />
Washingt<strong>on</strong>, DC 20005<br />
APhA (202) 628-4410 http:itwww.APhAneLorg