Bioidentical Hormones - U.S. Senate Special Committee on Aging

Bioidentical Hormones - U.S. Senate Special Committee on Aging Bioidentical Hormones - U.S. Senate Special Committee on Aging

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Post-WHI: Additional Issues Are hormone effects different if started immediately after menopause? - Secondary analyses of combined WHI Trials * Women starting hormones close to the menopause may have fewer heart attacks and deaths compared to the increases in women distant from the menopause * Stroke and breast cancer increased irrespective of years since menopause * Provides some reassurance that younger women using hormones for the short term for relief of hot flashes and night sweats are not at increased risk of heart disease * Older women with hot flashes and night sweats are at high risk if they start hormone therapy - Ongoing surrogate outcome trials (imaging studies of coronary and brain arteries) in younger women - Findings should not be taken to imply that any early benefit for coronary disease will persist into older ages * Would estradiol have had a different effect? * Role of route of administration (ltransdermal versus oral)

Statement of the American Pharmacists Association 230 On ong>Bioidenticalong> ong>Hormonesong>: Sound Science or Bad Medicine? Before the ong>Specialong> ong>Committeeong> on Aging United States ong>Senateong> April 19, 2007 American Pharmnacists.Association 1100 1 5 th St NW ,4oJ . Suite 400 Washington, DC 20005 APhA (202) 628-4410 http:itwww.APhAneLorg

Statement<br />

of the<br />

American<br />

Pharmacists<br />

Associati<strong>on</strong><br />

230<br />

On <str<strong>on</strong>g>Bioidentical</str<strong>on</strong>g> <str<strong>on</strong>g>Horm<strong>on</strong>es</str<strong>on</strong>g>:<br />

Sound Science or Bad Medicine?<br />

Before the <str<strong>on</strong>g>Special</str<strong>on</strong>g> <str<strong>on</strong>g>Committee</str<strong>on</strong>g> <strong>on</strong> <strong>Aging</strong><br />

United States <str<strong>on</strong>g>Senate</str<strong>on</strong>g><br />

April 19, 2007<br />

American Pharmnacists.Associati<strong>on</strong><br />

1100 1 5 th St NW<br />

,4oJ . Suite 400<br />

Washingt<strong>on</strong>, DC 20005<br />

APhA (202) 628-4410 http:itwww.APhAneLorg

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