Bioidentical Hormones - U.S. Senate Special Committee on Aging
Bioidentical Hormones - U.S. Senate Special Committee on Aging
Bioidentical Hormones - U.S. Senate Special Committee on Aging
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179<br />
EPVECTS OF POSTM4ENOPAUSAL ESTROGEN<br />
advior board for tIlly. Merch, and Procter rod WHI Rerestlgatod,<br />
Canthte.<br />
Robert<br />
Dr So<strong>on</strong><br />
D. L<strong>on</strong>sger. Miochel<br />
c.a-ved<br />
H.<br />
rendrshsp<strong>on</strong>ft<br />
Cnqrcr. Gregory<br />
his<br />
T. Ta-<br />
PragneamOfic Natia<strong>on</strong>al Heat, t<strong>on</strong>g, and Bland tolvrCedoc F. Gaarlan. Bt. Elain Hans<strong>on</strong>i: IlUae--<br />
ProrneradGambteand erknorsohnProc. niotet. Bethesda, Mdl: Barbara Aho.g Leslie Fred. srtyef Crtmlnefl. Clnchtvoti. Oblol Magery<br />
tee aod<br />
Can.<br />
orrstle.<br />
So.<br />
Drta.Cooctrh. mrscdedarjtf red/or Lemmrtce iemdma.eooary Gnlle. theLadll .. arre. teen rane<br />
accepted<br />
Werohe,<br />
trov-rarr<br />
Nebso WAtR;<br />
to, CME<br />
I.-shieny,<br />
sperkiaengae<br />
0f Ploard,<br />
nt McGnwan, Nancy Mords Visian Pann. LInda Pot- Grlneossteulclisnasllr<br />
sp<strong>on</strong>ord by Wyeth, Re-Weand<br />
Macian Linsachor.<br />
G-nsle.<br />
Michael<br />
Merck, and tea., Jacqar . Bossoo . .<br />
Peso. Andre flaarita.<br />
Pines:<br />
B.<br />
she is<br />
SU.n Williaynss<br />
also coretly<br />
Yv<strong>on</strong>n<br />
apdanclpa<br />
SMo.<br />
itrnvetiaorn` Clh~rol Caaaddeaftteg nterm (Frod Hitchern C<strong>on</strong>- sea; P.nversily,<br />
a Pfar-s1p.n-d<br />
at HawaI, Harolalol<br />
tool of a<br />
Dantd<br />
teateret<br />
Coab,<br />
for osepooa Resarh Centet Seantle, Wash) Romss L. Pantie, Heboi Pehmtch Beolit Bodogaa,<br />
rots sac l<strong>on</strong>ger<br />
flamal<br />
has<br />
Masaki,<br />
recnda research sappors fJn Cornet L RAdeesoo. Andre Z. La.eoi, Chades Santosh Shar<strong>on</strong>a; llUniverrsiy ottawa. Jo.. City/<br />
Wyeth red Organ<strong>on</strong> and seeved h<strong>on</strong>ororra fr<strong>on</strong> Or KBpoyesheg. Barbara Cochrane, Acme, McTier-<strong>on</strong>. lo Gavenposcl Bbest Watace, lame To-se, Sosen.<br />
snord or the spekers horeso far hoka.y, Mooarch. Je.NtM. Lesley Tmkr,,,C. Y. W<strong>on</strong>g. Cha Ch.n, Deho- Johns<strong>on</strong>, Linda Snettela.s, crartlyV.Vao<strong>on</strong>ho;y(Ues.<br />
Borg. and 0Onho-McNed, Dr Leni has receivd - rob Bfooee AL.n Kcriot Bath Poceso. Jl.net Stan. ,,n, yatOf asoorhasestFalbe. Clinic.<br />
seard,<br />
Wrcest.)<br />
giant<br />
Jo-<br />
trrr titiy. N-nrto. and Pf .e. Orwac- ford. PNte WeI.. E.*tj WtRle, pWAhe Lived Umcesty, didthOckene,Mtlagns, Rl.a Ira Wceise, RobedttYod.<br />
tovcsioWeode has received peahing h<strong>on</strong>oraia trm School at Medidine, Winst<strong>on</strong>-Solem. NQC Sally She. Pat<strong>on</strong>a A,--;s<strong>on</strong>.1-ioeroy, of Medici nerd Get-<br />
Merck and research sripport from, Wyeth.<br />
maher, BR-Id Pnvar, Michelle Nooghtrta: IMednal tohy oflt- enseoy. Ncwvokl N<strong>on</strong>nn<strong>on</strong> Laswer BoIjirde,<br />
CnerPOdeac: GarmeLt anders<strong>on</strong>, PhrD, M-Il Cthir Beseorch tabs, Highland Heights. KY) Eo<strong>on</strong> Sthein, Pc- Siogh. Ver Lesse, lobs Kosto; (LcrocediyottMia-,<br />
cat Co<strong>on</strong>daratiog Ceotet. Fred Hatchnsoe Caoer Retertatskoeeakc llhore-tyatCahf-rs at S.n F-an Miami, Fla Mary Jo O'Saban, Llrdc Poster, B. Essearch<br />
Center. I lOG Fasre Ave N. M3-A,110, Boo c~owl Stere Caasmctgs. Michael Nestit, Maice tape, D- eano esoam (LJsdnetltyOtdhoseta. Mei.-<br />
19024. Seattle, WA 90109 Igacoet*Nst-agl. Docloee.l~l: (-derOyftMinnesota. Mi<strong>on</strong>eapobisI Lbsa deapaolcorns L. Magichr, Richad H. Gamin, D<strong>on</strong>-<br />
Moore Lrnanher. MD. Dlsno. . Caadnotoolae math H.-sck; IbtWesos Bio*Snces Rockodle. Mdl Franh ate 0. Haivngbake. lane LaValleor Sarh eprr.<br />
rhise, Uoierrt oft FtOrtda Health Science Cernte. 1600 Coinnnrano Steve Lridentehcw lUiaceity at Wash- Itb<strong>on</strong>eard at Nvvado Beoo) Robert Br-or, Wri.<br />
SW Archer Rd. no<strong>on</strong>ts M409. PO R<strong>on</strong> 100277. CG s Ingt<strong>on</strong>. Seottlel Bnce Ptoy .lra Hmrkber. leer Graettogee, Vicki 0jevolk: IUeiersity at North<br />
od.FL 3l26t0-0277 (lkraercroedckreidt ledut. Cltnicat Centeert tAllied Biertelo College of Medli- C..4.no Chapel HISl Gierrdo Helora. Pamela Homes.<br />
Repeants: The W0)41 Cial CorennahR Centec, Di. One, Br<strong>on</strong>a. NY) Syhinl Warretthid-Snoaller, Willism Doseid Ontite. Coda hose, (Enk Wells (LtoIveity, of<br />
ashen of Pobb lfealts trncs Frd othiroto Can- PFsbnsa, odorhWyleie.Basen DkJa Baad, Bath Free Pittsburgh. Piotsghrrg. PAl Lends K.Ren Lane Coa~ley.<br />
cer Research Center, I tOO Faivlew Ace N. MI- iva; (SyofaCollegenlhlMedrcror. Hoast<strong>on</strong>. Tw en 6- N. Comb, Milan: (Unvemity ot Toe,,essen. Memythis)<br />
A410, PO Boo t9024, Seatlte, WASBIO09-1524. nie, Hays, R<strong>on</strong>ald Voag. Jill Anders<strong>on</strong>. Sandy Lith- Bares C. lahsn-, toane Satoeriebld, Ray<strong>on</strong>d W,<br />
Aotirr C<strong>on</strong>tedntbottoas As copritocipal i-osbigatoe ot gore. Pasil Bry. IBrightm And Womens Hospitat, Be, Fra Tytarsky. Steph<strong>on</strong>ie C<strong>on</strong>nrelly; ltinb1,nty ol<br />
the WHIf Coastcal Coordirsaing Center. Dr AndersOo H-eard Medioal SchsoLI Bosto. MasshoAss Man- Team Health Science Center. San Aret<strong>on</strong>so Robert<br />
had hot aces to aft at tse data rn the stody and tabes sort. lite Borntg, J. Moichael~izanaa, Kattryn Rearode. BraYthI. Robedt cheoken, late Traba, Mercedes Be-<br />
resyoslndty hoe the ntegilty at the dot, and the ac- C1oadla Char; (cr<strong>on</strong> thsvearnp. Procfdencei llAtn dogrr.tSdoentes ChadesMaolnr(nhlc"vr lol Wit.<br />
cwaray of the dota aVAyo.<br />
tease R. A.Ml. CoasI Waseler. Chaites Eat<strong>on</strong>. Michofto ca.ivi, Madis<strong>on</strong>,) Gloria Sadto, Goglor Look,. Pa-<br />
Sh.rr c<strong>on</strong>cept <strong>on</strong>d clescgri Anders<strong>on</strong>. Blank. Coa. Cy,; ttmary Uhscersity. Atlanta. Gal L.o<strong>on</strong>ece Phrdt trid, Madde. col Msoact'redirsa, Baara- tao<strong>on</strong>gier;<br />
Cater. L<strong>on</strong>ger. Lever. Maris<strong>on</strong>, Morgok. Prentice, ipr. Margart Pedeimo.. Ora Stdckland. Mgargave (Wake Forest Umoamly, School at Medicrns. wiest<strong>on</strong>-<br />
Bobbins. Rossoom. Stfefoowk, Wartacki-Wendc. Hahee,. Vhtra Porter, (Fred Halchtesoa Cane Re- Saeles, NC) Denise B<strong>on</strong>rdr. Cmg Bathe, Boola C-os,<br />
Weallace.<br />
search Center. Snattle, WashI thidey A A, cecos- Moso Viotes, tortt Waobho; IWaym Slate Uro.<br />
Acooroitian of data: Anderso, Limarhel. Asset. Joir, Vichy M. Taylor. Nanc F. Woods, Macten stnity, (chord of Medrclse/Hfotca Hospitalt Detroit<br />
Bassord. BersArd. Olack. Roads. Oniener, Braysbi. Henders<strong>on</strong>. Robyn A.den.,. (George, Washingt<strong>on</strong> Mich)lS..r Heodd, Michaeil Sv<strong>on</strong>. Georlneclemky.<br />
Coas. Chlehomsbt. Cork. Cars. Hays. Heks. Heeddct, lUrsersiy. Wahklt-gaa CC) Jldith He,Ja Narty aaba, Dtodrs Wtaey M<strong>on</strong>itorngecBo& aedsetWdbes(chd,)<br />
Homad. Hsts. Hubbell, Jackna.lbs<strong>on</strong>, ) thntsheo. 1o00 A-.-sa; (MaHer ,UCLA Resarch and Edoco ogeBr<strong>on</strong>wold, Hia,,ey Cohen. Ehabeth Barrtt-<br />
Kater. LoCraia. t<strong>on</strong>e. L<strong>on</strong>ger. Lass-, Lens. M.nso, U. Insbrtet. Toanaie, Calt) Roman Chlebmasnrl. BRb. Cm . Gooid Deoaets, too Go<strong>on</strong> ).ha.- Dwye.<br />
Margohas, Ockene. O'Sallrcan. Phillips, Prentice, ed Getravo, Aoor Nels<strong>on</strong>, JIsoer Heinee Jh<strong>on</strong> Mar Robert P- Heaney. Dahet Mars<strong>on</strong>, VItnor Vogel, Le-~<br />
Bitenboogh Bobbins. harts. Stet<strong>on</strong>ich. Van Hor., thaI, lgosotProacrte CenterfarHp.th Roercbl,<br />
ROY Wacinsd. Satins stand<br />
W.oCt-wshtWende. Wallace, W-Assheil-Sanoller POih<strong>on</strong>d,.OreClmyIoFiteobaoghs. tatharaVoholr.<br />
P<strong>on</strong>dhg/Sppot<br />
Analysis<br />
Pa-<br />
arod Bate of the Bp-.so Tho Na-<br />
and interpretatlioo of data. Andors<strong>on</strong>. fMd. Ete-et Victor St~eves, HJeA Baroeia; yca.se<br />
tienal Heart Lan& and Bred 1osotte lONtHLl tands<br />
Llmacher, Oeeestord, Black. Beoe.Bayshi. Pmrnan~eatesn<strong>on</strong>ol Rsearct, Oakdcr. CahlfelBO the WHNI PIogsam The NI-HLcI P.paro led or he do.<br />
Cea_ Stephen Sidnrey. tuee Boaily.ccvneHihataloaede<br />
Icicd, taCavin. anger. Le-is. Macs<strong>on</strong>. Margotis, eol Cnltegectolo<strong>on</strong>in.J Mihoak~e. W.) rov tens.<br />
the data and this report One PNHLBI sepreseolthn<br />
Ockc<strong>on</strong>, Prentice, fRassoa., Stetanich. Wallace, try Kccmrra V<strong>on</strong>sr BanrabeLTheodarrdA.<br />
serces ar meebe,<br />
flothen,<br />
of be Whit Steevig Coenitce<br />
WoSserthell.S-rrrfo<br />
Mary Aci C. Girhgan. )a- Heave, lteedbtar<br />
and wrftg<br />
Be-<br />
grosi Wyeth peeded sldy pilh lach<strong>on</strong><br />
Graftegof the e<strong>on</strong>s-opt Acdesa.-L--ahee Cork. serh tnb-tateH<strong>on</strong>ad U.Nversity. Worhiogtre. DO)<br />
and placehol hte hod en nther rote In the 9ndy.<br />
outer, LoCroic. L<strong>on</strong>ger. Prentic..<br />
Barbara V. Homod, L,,n~eAdrem.Canspbrl,<br />
Ashnomldg-iset<br />
Loo-n~en<br />
We grotetoly osh<strong>on</strong>-tedge the<br />
Crabal rev/pen of ahe -manrpt for important in.<br />
dedicated<br />
Lsin.~<br />
efforts<br />
M<strong>on</strong>iqor<br />
at investIgatr<br />
Baintord,<br />
end<br />
Gabrel<br />
olffat<br />
UaSo;a<br />
the WHI<br />
lflornh-<br />
tellecloalcolent. Anders<strong>on</strong>. Llmache. Assat. Bassytem, Ufnherity. Chicago, [R1 Linda Van Ham.<br />
clinical<br />
Phibyp<br />
centers, the WHI Clinical Coordisahog Cetoad.<br />
BcIMs'r. Blclskh, B<strong>on</strong>doRe. s Baryshi. Corn, Craenl<strong>on</strong>d, larardan Ichadeko.,<br />
to, and the<br />
Brang<br />
NHLBI pregra<br />
Li., Carat<br />
aclice ltshg-acabaheot<br />
ChfteliA ohCor Casm<br />
httpJlrcw<br />
Hays,<br />
hic.ncoogl<br />
He.is<br />
oisd<br />
Hendila.<br />
especially<br />
Heoord<br />
May Pett.gee<br />
Rosenbe&Rg hiohPrrsyteiaSt LiskeshledaaCe- hoe rtoirssei analysis adSeiGovsfrars<br />
Heis. rnitrell. cockoo. Jhasn., hcida, Kcobcthn. .idler tot Chicago, I1M Heny clock. Lyrsdr Powell. E~le.Mo- lanice or the prepas<strong>on</strong>d ofted ivvn op, tere i-<br />
LaCrola, Lane, L<strong>on</strong>ger, tossier. Lewis. M<strong>on</strong>s<strong>on</strong>. s<strong>on</strong>, IStanford Preneok OeRarch Cener Stant<strong>on</strong>rd<br />
MaItigoe Ocken. O'Saltnan, Phillips. Bitenkoagh.<br />
porlantly, me want to<br />
University.<br />
recognian the<br />
Starstord,<br />
WHI padiila<br />
Cabll MarCIAL. Stetevick, Mark<br />
Bobbins. Rossoam, tasty, Stelaniick, Van Horn,<br />
parts for thhel Orhaodlnay c<strong>on</strong>rmibnsenlt<br />
A. Hlathy. Orrtsa<br />
t theWHIt<br />
Chen, Randall h. Stafford. Linda C.<br />
Woctstinshr.Wcod. Wallace. Wrs-erhedt-hrnioer. Giodice, (State Uo<strong>on</strong>anyof tN-Yocaat Stoy<br />
progra..<br />
Boakl<br />
llatrbshicalanalsiV Anders<strong>on</strong>, L.oCrIoc. Prentc.. Dorothy tree. hits 0G10k, oilllam Lasso. Gah<br />
Obtained hotdosg Aridees<strong>on</strong>. Assaft Block Br<strong>on</strong>er, Uavo<strong>on</strong>ian CalbednnMessina: CtheOhiv, tlte Um.<br />
Coth. Heirs, Hendno. Lay,. L<strong>on</strong>ger Lends, Macs<strong>on</strong> newly, CatoorhoS) Bebesca Jacks<strong>on</strong>. Randall Horns.<br />
htorgnRs, Osckne. Philips, Frentc. Rokbbins,Basn-c, Eleocra Poshest.W 60. ery Mysho. MIchoel Blamen. 1.<br />
Stetasick,<br />
Stamnpfer<br />
Woccawsksh-oene.<br />
M. Coldila G. Estrgenreplactn<br />
Walbece. Wasserhed- feM, (L;ZoNer at Alabaa at Birevoam Cm. F. therapyarrd<br />
Smatter.<br />
codinory heart diseas a 500rtibats as<br />
tense, Albiert Obennan, lame M. Stobrey. Morlb<br />
Aditmioltralie technia.-omtvacyor<br />
siesoet at the eprdeesatogic<br />
dr<br />
evidence. Pre Med.<br />
Saford<strong>on</strong>a BA .00fF; (liniverrty, at Aneana, bars<strong>on</strong>,<br />
oaoAssaf. Rassfoed. Bresoed. ec, Black,<br />
19'91.200.7-03.<br />
rBiaysks, Phoenil. Toaisn Bastord, Cyndl Thomsn,. Marcia 2. cash yT, Barren<br />
C.ab.<br />
-C<strong>on</strong>no<br />
Hays.<br />
E. Cowan<br />
tier.<br />
LG,<br />
Hnerdv,<br />
at at. Ca-<br />
Ho.. d,tHeirHhbebLkaclr. IKo. Are MMrl Loser.lt renl at Bi8l.1 Botlalo dl<strong>on</strong>ascolar re<strong>on</strong>ablly, and n<strong>on</strong>c<strong>on</strong>traceptis<br />
a. lohos<strong>on</strong>,.<br />
-<strong>on</strong>ea es-<br />
tcloen. coder. L<strong>on</strong>ge., Lesss Manam. NY) lean WaidawsIdwende. Ma-160 Tweo-sa, Eke.<br />
Macga1.,<br />
togerinmornen<br />
Prentice.<br />
-Wses<br />
BRienlragf,<br />
fra the LUped.doeeaCh.l-<br />
Bobbins. ROScOo. hs~t,Shnc-Grham,Jlove Choog (Un-itesy o ato. <strong>on</strong> Pee-rfor Whim-p shidy.<br />
S<strong>on</strong>yo.<br />
Cirrata<strong>on</strong>.<br />
Slenanlob, WactassloWerrde.<br />
1907:75:<br />
Wallace, tama at Grass S.--aeoto loh Ro4hols, S. Tar<br />
Stop<br />
t502-tt09,<br />
laPyivicen: Ansat, Reesord, Block Barir mee: (U.Nrersity at Cobtomi allel, Or<strong>on</strong>gel At. 3. Crady G. Rathe SR, Petthol DS, e atHomn<br />
Orayslo, Can, Chtebowskn. Cork, Hays, was. Heendfi.. [<strong>on</strong> HobheR, Carl Frak, Batban Wang. Nancy Crep. therapy to presrt diseasei and prlotog tile<br />
1-1nward.<br />
In pvtt-<br />
HSla.. dOasr. lohosomn lod. Baler. LoCasa, Bradley Mcok; (U.eiertly, at Califo~ivi at Los dage meNopose wom ndn<br />
Latte.<br />
blteat<br />
Bit-eohaat.<br />
Med. 1h92;517:<br />
Robbrnn, Bass-a. Van Horn, torI Howard hdod, GD.dHober. Rohert~lahntlf;lUrn<br />
WacnaodlcW.Wrnd. Wallace.<br />
10th-tO37.<br />
,versdyrt1CatnoinmothS. Dirge, LalfaIoChalaVndt. 4& Deport 6G. Page Ct, Mrnopsaol estrogen e-<br />
t22i0r4 Amrcricorr, Medical A.Sssciatsrr. All vtghts, resen-ed. (Reryintrd) lAMA, ApciI I, 2it4-iR.1~v201,N,r4.. 1i 711<br />
n<strong>on</strong>rloaded fixrom ac-sv)arrs, o at Natoalot fisoattte of Ftlls, or April 16, 2007