Bioidentical Hormones - U.S. Senate Special Committee on Aging

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prescribe natural hormones but who aren't familiar with the fact that hormones should
mimic your natural hormone rhythms will merely prescribe natural hormones in the same
way they prescribe synthetics. The Women's Health Initiative has already found the
Standard of Care to be dangerous, what if it's not just the synthetic molecules that are
dangerous?
Or, conversely, what if it's really the missing rhythm that matters?
The Wiley Protocol
I decided it was all three, the molecule, the delivery system and the timing. I
devised a dosing schedule accomplished in 3cc capped syringes with 30 lines on the each.
An average I month prescription has nine syringes of estrogen and nine syringes of
progesterone. The hormones are dosed in "lines" on the syringes. The dose escalates
every three days to address the issue of 72 hour "receptor roll-over". In other words, we
wait for the receptors for the hormones to catch-up to the dose before raising it each time.
The Basic Wiley Protocol® -dosing schedule is the same starting point for all women
using this method of BHRT, but it can be individualized by raising or lowering the dose
ofe ltueii hormone by 2 lines in a 28 day period or making more amplitude by raising the
dose of the appropriate hormone two more lines on the peak days of Day 12 and Day 21.
The formulation and manner of dosing bio-identical HRT started out as a "thought
experiment" in my book, Sex, Lies and Menopause. In the book, I asked the question - "if
hormone replacement was made of real bio-identical hormones and dosed to mimic the
ups and downs of the hormone blood levels in a normal menstrual cycle in a 20 year-old
woman, would all of the symptoms and disease states of aging decline or even,
disappear?"
Well, so far we have watched over a thousand women here in Santa Barbara and it-
looks like the logic holds - because it was the rhythm that was always missing in other
regimens. I asked the doctors to prescribe no more than 3 months at a time and require
blood tests of estrogen and progesterone at month 3 on the peak days of the cycle to see if
we had attained the levels in serum blood work for a woman twenty years-old, or if we