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Bioidentical Hormones - U.S. Senate Special Committee on Aging

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102<br />

Bio-identical progester<strong>on</strong>e replacement is a shoe-in as a cancer treatment because<br />

cancer was never about cellular overgrowth. It has always been about not enough death--<br />

in the presence of overgrowth. But cutting edge medicine has never equated menopause<br />

with cancer, even though cancer strikes at the time in a woman's life when her horm<strong>on</strong>es<br />

are disappearing. The Standard of Care treatment plan is to further remove her estrogen.<br />

Taking estrogen away from women, or selectively blocking it without ever c<strong>on</strong>sidering<br />

the synergy between the estrogen and progester<strong>on</strong>e, the most selective potent apoptotic<br />

factor known in the human body, is not the way to eradicate cancer.<br />

It's the way to cause heart disease and Alzheimer's.<br />

Are They <str<strong>on</strong>g>Bioidentical</str<strong>on</strong>g> <str<strong>on</strong>g>Horm<strong>on</strong>es</str<strong>on</strong>g> Bio-identical or Not?<br />

Even natural bio-identical horm<strong>on</strong>es are not bio-identical unless your body can<br />

recognize them as horm<strong>on</strong>es. Since natural horm<strong>on</strong>e replacement is possible, the other<br />

half of the questi<strong>on</strong> is how to take bio-identical horm<strong>on</strong>es? The scientific studies looking<br />

at the differences in Oral (by mouth) and Transdermal (using a neutral cream base as a<br />

carrier of the horm<strong>on</strong>e) show significantly less side effects when horm<strong>on</strong>es enter the<br />

bloodstream through the skin and fat base barrier just like Type Is take insulin. So<br />

through the skin is "how". What remains is "when". Replacement is not replacement<br />

unless you truly replace what has been lost.<br />

The idea that horm<strong>on</strong>e "replacement" could be affected by a <strong>on</strong>e time a day, same<br />

dose every day regimen is illogical. The hallmark of an endocrine system is pulsitilty and<br />

amplitude, meaning that horm<strong>on</strong>es pulse every few sec<strong>on</strong>ds and their amounts go higher<br />

and higher, depending <strong>on</strong> the time of the m<strong>on</strong>th in the case of estrogen and progester<strong>on</strong>e.<br />

So it seemed to me that the way to achieve HRT with least side-effects was to use a bio-<br />

identical molecule for both horm<strong>on</strong>es, transdermally, in doses that could increase and<br />

decrease over time.<br />

Natural horm<strong>on</strong>es are not bio-identical unless they replace precisely the "natural"<br />

rhythmic levels of your own estrogen and progester<strong>on</strong>e when you were a young woman.<br />

Currently, the standard horm<strong>on</strong>e replacement therapy you would receive from a doctor<br />

would be PremPro, or Premarin, if you've had a hysterectomy. And doctors who want to

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