BioSciences - Polysciences, Inc.

Polymers
Poly(ethylene glycol) / Poly(lactic acid) Diblock and Triblock Polymers (PEG/PLA) HU4bg
Polymer structures featuring polyethylene glycol (PEG), with biodegradable or biocompatible
segments offering micellular, nano and microsphere morphologies which are useful for controlled
release formulations . Molecular weights of blocks controlled by GPC . Alternative
structures can be synthesized .
Historically there have been three basic building block monomers for degradable polymers: lactides,
glycolides and caprolactone . All are in clinical use and show varying degrees of degradability based
on backbone compositions, crystallinity and molecular weights .
Lactic acid is a “chiral” molecule having both (L) and (D) forms with (L) being the common metabolite .
The family of lactic acid polymers includes the pure poly-L- lactic acid (L form of PLA), the pure poly-
D-lactic acid and the poly-D,L-lactic acid (DL-PLA) . Many other useful compositions occur when the
polymer is organized into diblocks with ethylene glycol and/or glycolic acid comonomers or triblocks
with ethylene glycol and/or glycolic acid .
Catalog Size
Diblock Polymers (numbers in parentheses refer to the Mw of the segment)
PEG(350)-b-PLA(300) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24375-0 .5 0 .5 g
24375-1 1 g
PEG(1,000)-b-PLA(750) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24378-0 .5 0 .5 g
24378-1 1 g
PEG(1,000)-b-PLA(5,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24381-0 .5 0 .5 g
24381-1 1 g
PEG(5,000)-b-PLA(1,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24386-0 .5 0 .5 g
24386-1 1 g
PEG(5,000)-b-PLA(5,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24389-0 .5 0 .5 g
24389-1 1 g
PEG(5,000)-b-PLA(10,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25018-0 .5 0 .5 g
25018-1 1 g
PEG(10,000)-b-PLA(5,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25017-0 .5 0 .5 g
Triblock Polymers (numbers in parentheses refer to the Mw of the segment)
25017-1 1 g
PLA(1,000)-b-PEG(1,000)-b-PLA(1,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24500-0 .5 0 .5 g
24500-1 1 g
PLA(2,000)-b-PEG(1,000)-b-PLA(2,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24501-0 .5 0 .5 g
24501-1 1 g
PLA(5,000)-b-PEG(1,000)-b-PLA(5,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24502-0 .5 0 .5 g
24502-1 1 g
PLA(1,000)-b-PEG(4,000)-b-PLA(1,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24503-0 .5 0 .5 g
24503-1 1 g
PLA(1,000)-b-PEG(10,000)-b-PLA(1,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24509-0 .5 0 .5 g
24509-1 1 g
PLA(5,000)-b-PEG(10,000)-b-PLA(5,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25026-0 .5 0 .5 g
25026-1 1 g
PLA(10,000)-b-PEG(10,000)-b-PLA(10,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25027-0 .5 0 .5 g
25027-1 1 g
Poly(ethylene glycol terephthalate) [25038-59-9] H2g . . . . . . . . . . . . . . . . . . . . . . . . . . . .
TSCA
(-COC 6 H 4 COOCH 2 CH 2 O-) n
Polymer widely used in films, fibers, and drink bottles .
Low gas permeability .
04301-250 250 g
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