BioSciences - Polysciences, Inc.

Polymers
Poly(tert-butyl methacrylate) [25189-00-8] U4g . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Tg 107° [-CH 2 C(CH 3 )[CO 2 C(CH 3 ) 3 ]-] n
Hard, thermally sensitive, methacrylate ester . Decomposes thermally to poly(methacrylic acid) .
Polycaprolactam [25038-54-4] A2g
(Nylon 6) mp 215-250° n 20
D 1 .530 TSCA
Widely used in fibers .
Catalog Size
MW ~18,000 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18180-250 250 g
MW 35,000 4 .1 rel . visc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18179-250 250 g
Polycaprolactone [24980-41-4] H4g . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
MW 43,000-50,000 mp 55-65°C TSCA [-O(CH ) CO-] Form: ~3mm
2 5 n
pellets
Biodegradable polymer, hydroxyl end group .
O ( CH2) O
C
New! Polycaprolactone, powdered [24980-41-4] H4g . . . . . . . . . . . . . . . . . . . . . . . . . . . .
MW 50,000 mp 58 – 60°C TSCA [-O(CH 2 ) 5 CO-] n
Biodegradable polymer, hydroxyl end group .
Polycaprolactone diol [36890-68-3] H4g
d 1 .07 TSCA
H[-O(CH 2 ) 5 CO-] n OCH 2 CH 2 OCH 2 CH 2 O[-CO(CH 2 ) 5 O-] n H
Biodegradable polymer . Can be used to make block copolymers .
MW 1,250 mp 45°C liquid Viscosity 65-100 cps @ 55°C . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 09706-500 500 g
MW 2,000 mp 50°C liquid Viscosity 530-730 cps @ 55°C . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 09694-500 500 g
Poly(ε-caprolactone)-block-poly(ethylene glycol) - Diblock and Triblock Polymers
Among the leading candidates for biodegradation are caprolactone based materials due to their
approved uses by the FDA for drug delivery systems, sutures, long term implants and adhesion
barriers as well as new tissue scaffold host systems .
Caprolactone is a biodegradable polyester with a relatively low melting point (60° C) but a glass
transition temperature (Tg) around -60° C . The high crystallinity in the polyester accounts for this
property balance . It is made by metal catalyzed ring opening polymerization of epsilon caprolactone
. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons . By
comparison, a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of
+55° C and a melting temperature Tm of about 175° C .
Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock
(A-B-A) copolymers with polyethylene glycol . Synthetic methods which lead to block structures allow
the polymer to have controlled biodegradation rates as well as improved physiological compatibility
characteristics . Additional custom synthesis materials are available upon request . Please contact us
for a quotation for your custom synthesis needs .
07037-25 25 g
Diblock Polymers
H
O n
O
m OMe
Numbers in parentheses refer to Mw of the segment.
O
PCL(1,000)-b-PEG(1,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25010-0 .5 0 .5 g
25010-1 1 g
PCL(1,000)-b-PEG(2,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25011-0 .5 0 .5 g
25011-1 1 g
PCL(1,000)-b-PEG(5,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25012-0 .5 0 .5 g
25012-1 1 g
PCL(5,000)-b-PEG(1,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25022-0 .5 0 .5 g
25022-1 1 g
PCL(5,000)-b-PEG(2,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25023-0 .5 0 .5 g
25023-1 1 g
PCL(5,000)-b-PEG(5,000) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25024-0 .5 0 .5 g
25024-1 1 g
5
n
19561-500 500 g
25090-500 500 g
For more information please call (800) 523-2575 or visit: polysciences.com 183