89-91 - Polskie Stowarzyszenie Biomateriałów

fIg.5. microscopic view 2
weeks after implantation
of tested hernia mesh
dallop® m into subcutaneous
tissue. Samples
of mesh with the band
of loose rich-cell connective
tissue. Stain hE.
magn.140x.
fIg.7. microscopic view 2
weeks after implantation
of control hernia mesh
duramesh tm into subcutaneous
tissue. on the
top the samples of mesh
surrounded by the band
of loose rich-cell connective
tissue. Stain vg.
magn.280x.
fIg.9. microscopic view 2
weeks days after implantation
of tested hernia
mesh dallop® m into muscle
tissue. In the centre
the samples of mesh with
the loose rich-cell connective
tissue separating
them from the skeletal
striated muscles. Stain
vg. magn.140x.
fIg.6. microscopic view 2
weeks after implantation
of tested hernia mesh dallop®
minto subcutaneous
tissue. Round fibres surrounded
by the band of loose
rich-cell connective tissue
with visible eozynophils.
Stain hE. magn.280x.
fIg.8. microscopic view 2
weeks after implantation
of tested hernia mesh
dallop® m into the muscle
tissue. on the bottom,
the samples of mesh surrounded
by the band of
loose rich-cell connective
tissue; beside the skeletal
striated muscles. Stain
vg. magn.140x.
fIg.10. microscopic view
52 weeks after implantation
of tested hernia
mesh dallop® m into subcutaneous
tissue. In the
centre the samples of
mesh, surrounded by fibre
connective tissue. Stain
hE. magn.56x.
tested as well as control mesh. From minimal quantity, in
the form of single cells accompanying fibrosis, to a few fat
layers separating the implant from surrounding tissues. It
must be emphasized that the complete healing in process
probably has no finished and insignificant inflammatory
process still take place mainly between filaments of the
tested meshes.
In the employed semi-quantitative score evaluation comparing
the tested mesh Dallop® M with mesh Duramesh TM
only in the subcutaneous tissue in test period of 2 weeks
the result obtained showed slight irritating effect. In further
evaluations of subcutaneous tissue reaction namely after
fIg.11. microscopic view
52 weeks after implantation
of tested hernia
mesh dallop® m into subcutaneous
tissue. In the
centre the samples of
mesh, surrounded by fibre
connective tissue. Stain
vg. magn.140x.
4,12,26 and 52 weeks the result was obtained proving lack
of irritating effect. Due to the fact that this result only concerns
the subcutaneous tissue, where the samples were
implanted and despite using suture for fixation the samples
displaced, and the period of only 2 weeks it is probable that
irritation was the result of sample displacement. In all test
terms in muscles the mesh Dallop® M compared to mesh
Duramesh TM showed no irritating effect.
Conclusion
fIg.12. microscopic view
52 weeks after implantation
of tested hernia mesh
dallop® m into subcutaneous
tissue. The rich-cell
connective tissue in the
straight neighbourhood of
the fibre of mesh is visible.
Stain. vg. magn. 560x
fIg.13. microscopic view
52 weeks after implantation
of control herniamesh
duramesh tm fIg.14. microscopic view
56 weeks after implantation
of control hernia
into subcu- mesh duramesh® into
taneous tissue. on the subcutaneous tissue. on
right, the round samples left I right side the round
of mesh surrounded by sample of mesh surroun-
the band of the fibre conded by the band of fibre
nective tissue with loose connective tissue. In the
rich-cell connective tissue straight neighbourhood
between filaments. Stain of the fibres of mesh are
v.g.. magn.560x. visible inflammatory cells.
Stain vg. magn.560x.
fIg.15. microscopic view fIg.16. microscopic view
52 weeks after implantation 56 weeks after implanta-
of tested hernia mesh daltion of tested hernia mesh
lop® m into muscle tissue. dallop® m into muscle
In centre, the samples of tissue. visible the rich-cell
mesh surrounded by thin connective tissue between
band of fibre connective the fibers of mesh. Stain.
tissue with fat infiltration hE. magn. 560x.
between the mesh fibres.
Stain. vg. magn. 56x.
- In histological evaluation in subcutaneous tissue after