89-91 - Polskie Stowarzyszenie Biomateriałów
89-91 - Polskie Stowarzyszenie Biomateriałów
89-91 - Polskie Stowarzyszenie Biomateriałów
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fIg.5. microscopic view 2<br />
weeks after implantation<br />
of tested hernia mesh<br />
dallop® m into subcutaneous<br />
tissue. Samples<br />
of mesh with the band<br />
of loose rich-cell connective<br />
tissue. Stain hE.<br />
magn.140x.<br />
fIg.7. microscopic view 2<br />
weeks after implantation<br />
of control hernia mesh<br />
duramesh tm into subcutaneous<br />
tissue. on the<br />
top the samples of mesh<br />
surrounded by the band<br />
of loose rich-cell connective<br />
tissue. Stain vg.<br />
magn.280x.<br />
fIg.9. microscopic view 2<br />
weeks days after implantation<br />
of tested hernia<br />
mesh dallop® m into muscle<br />
tissue. In the centre<br />
the samples of mesh with<br />
the loose rich-cell connective<br />
tissue separating<br />
them from the skeletal<br />
striated muscles. Stain<br />
vg. magn.140x.<br />
fIg.6. microscopic view 2<br />
weeks after implantation<br />
of tested hernia mesh dallop®<br />
minto subcutaneous<br />
tissue. Round fibres surrounded<br />
by the band of loose<br />
rich-cell connective tissue<br />
with visible eozynophils.<br />
Stain hE. magn.280x.<br />
fIg.8. microscopic view 2<br />
weeks after implantation<br />
of tested hernia mesh<br />
dallop® m into the muscle<br />
tissue. on the bottom,<br />
the samples of mesh surrounded<br />
by the band of<br />
loose rich-cell connective<br />
tissue; beside the skeletal<br />
striated muscles. Stain<br />
vg. magn.140x.<br />
fIg.10. microscopic view<br />
52 weeks after implantation<br />
of tested hernia<br />
mesh dallop® m into subcutaneous<br />
tissue. In the<br />
centre the samples of<br />
mesh, surrounded by fibre<br />
connective tissue. Stain<br />
hE. magn.56x.<br />
tested as well as control mesh. From minimal quantity, in<br />
the form of single cells accompanying fibrosis, to a few fat<br />
layers separating the implant from surrounding tissues. It<br />
must be emphasized that the complete healing in process<br />
probably has no finished and insignificant inflammatory<br />
process still take place mainly between filaments of the<br />
tested meshes.<br />
In the employed semi-quantitative score evaluation comparing<br />
the tested mesh Dallop® M with mesh Duramesh TM<br />
only in the subcutaneous tissue in test period of 2 weeks<br />
the result obtained showed slight irritating effect. In further<br />
evaluations of subcutaneous tissue reaction namely after<br />
fIg.11. microscopic view<br />
52 weeks after implantation<br />
of tested hernia<br />
mesh dallop® m into subcutaneous<br />
tissue. In the<br />
centre the samples of<br />
mesh, surrounded by fibre<br />
connective tissue. Stain<br />
vg. magn.140x.<br />
4,12,26 and 52 weeks the result was obtained proving lack<br />
of irritating effect. Due to the fact that this result only concerns<br />
the subcutaneous tissue, where the samples were<br />
implanted and despite using suture for fixation the samples<br />
displaced, and the period of only 2 weeks it is probable that<br />
irritation was the result of sample displacement. In all test<br />
terms in muscles the mesh Dallop® M compared to mesh<br />
Duramesh TM showed no irritating effect.<br />
Conclusion<br />
fIg.12. microscopic view<br />
52 weeks after implantation<br />
of tested hernia mesh<br />
dallop® m into subcutaneous<br />
tissue. The rich-cell<br />
connective tissue in the<br />
straight neighbourhood of<br />
the fibre of mesh is visible.<br />
Stain. vg. magn. 560x<br />
fIg.13. microscopic view<br />
52 weeks after implantation<br />
of control herniamesh<br />
duramesh tm fIg.14. microscopic view<br />
56 weeks after implantation<br />
of control hernia<br />
into subcu- mesh duramesh® into<br />
taneous tissue. on the subcutaneous tissue. on<br />
right, the round samples left I right side the round<br />
of mesh surrounded by sample of mesh surroun-<br />
the band of the fibre conded by the band of fibre<br />
nective tissue with loose connective tissue. In the<br />
rich-cell connective tissue straight neighbourhood<br />
between filaments. Stain of the fibres of mesh are<br />
v.g.. magn.560x. visible inflammatory cells.<br />
Stain vg. magn.560x.<br />
fIg.15. microscopic view fIg.16. microscopic view<br />
52 weeks after implantation 56 weeks after implanta-<br />
of tested hernia mesh daltion of tested hernia mesh<br />
lop® m into muscle tissue. dallop® m into muscle<br />
In centre, the samples of tissue. visible the rich-cell<br />
mesh surrounded by thin connective tissue between<br />
band of fibre connective the fibers of mesh. Stain.<br />
tissue with fat infiltration hE. magn. 560x.<br />
between the mesh fibres.<br />
Stain. vg. magn. 56x.<br />
- In histological evaluation in subcutaneous tissue after