PROGRAMM JAHRESTAGUNG 2012 30. Nov. – 2. Dez ... - ÖGDV
PROGRAMM JAHRESTAGUNG 2012 30. Nov. – 2. Dez ... - ÖGDV
PROGRAMM JAHRESTAGUNG 2012 30. Nov. – 2. Dez ... - ÖGDV
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Poster Psoriasis<br />
P 29<br />
The Therapeutic History of a Recalcitrant Case of Psoriasis Vulgaris<br />
Jenny Deluca 1<br />
Elena Polestra 1<br />
Nadia Bonometti 1<br />
Dunja Vigl 1<br />
Tobias Thuile 1<br />
Klaus Eisendle 1<br />
1 General Hospital of Bolzano, Department of Dermatology, L. Boehler Str. 5 I, 39100<br />
Bolzano, Italy<br />
Introduction: Psoriasis is a chronic inflammatory disorder with polygenic<br />
predisposition and triggering environmental factors. It comprise several clinical<br />
expressions, typical lesions are chronic, recurring, scaly papules and plaques. For most<br />
affected patients psoriasis cause a deterioration of many aspects of daily life.<br />
Methods: We present a case of a psoriatic 56 year old man, affected since the age of<br />
20. During its long therapeutic history he has tried, for almost the totality, the current<br />
disposable drugs. He started with conventional treatments: radiation (Bade-PUVA),<br />
followed by ciclosporin, methotrexate, then it switched to the biologics such as raptiva,<br />
etanercep and adalimumab. In any case of therapy he had a short time remission<br />
followed by a resistant relapse of disease.<br />
Results: As final therapeutic option we give the patient the latest approved biological<br />
drug, Ustekinumab, with encouraging results: a first unambiguous PASI response was<br />
already seen within one month of therapy and almost complete remission in 3 months.<br />
The patient is still in therapy.<br />
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