PROGRAMM JAHRESTAGUNG 2012 30. Nov. – 2. Dez ... - ÖGDV

Poster Psoriasis
P 29
The Therapeutic History of a Recalcitrant Case of Psoriasis Vulgaris
Jenny Deluca 1
Elena Polestra 1
Nadia Bonometti 1
Dunja Vigl 1
Tobias Thuile 1
Klaus Eisendle 1
1 General Hospital of Bolzano, Department of Dermatology, L. Boehler Str. 5 I, 39100
Bolzano, Italy
Introduction: Psoriasis is a chronic inflammatory disorder with polygenic
predisposition and triggering environmental factors. It comprise several clinical
expressions, typical lesions are chronic, recurring, scaly papules and plaques. For most
affected patients psoriasis cause a deterioration of many aspects of daily life.
Methods: We present a case of a psoriatic 56 year old man, affected since the age of
20. During its long therapeutic history he has tried, for almost the totality, the current
disposable drugs. He started with conventional treatments: radiation (Bade-PUVA),
followed by ciclosporin, methotrexate, then it switched to the biologics such as raptiva,
etanercep and adalimumab. In any case of therapy he had a short time remission
followed by a resistant relapse of disease.
Results: As final therapeutic option we give the patient the latest approved biological
drug, Ustekinumab, with encouraging results: a first unambiguous PASI response was
already seen within one month of therapy and almost complete remission in 3 months.
The patient is still in therapy.
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