PROGRAMM JAHRESTAGUNG 2012 30. Nov. – 2. Dez ... - ÖGDV
PROGRAMM JAHRESTAGUNG 2012 30. Nov. – 2. Dez ... - ÖGDV
PROGRAMM JAHRESTAGUNG 2012 30. Nov. – 2. Dez ... - ÖGDV
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Poster Tumore der Haut<br />
P 45<br />
The Prevalence of Primary Cutaneous Lymphomas at a Dermatology Referral<br />
Center in Lower Austria<br />
Andrea Kern 1<br />
Johanna Eder 1,2<br />
Melitta Kitzwoegerer 3<br />
Roland Sedivy 3<br />
Franz Trautinger 1,2<br />
1 Landesklinikum St. Pölten, Karl Landsteiner Institut für Dermatologische Forschung,<br />
Propst-Führer-Straße 4, A-3100 St. Pölten<br />
2 Landesklinikum St. Pölten, Abteilung für Haut- und Geschlechtskrankheiten,<br />
Propst-Föhrer-Straße 4, A-3100 St. Pülten<br />
3 Landesklinikum St. Pölten, Institut für klinische Pathologie,<br />
Propst-Führer-Straße 4, A-3100 St. Pölten<br />
Introduction: In this retrospective analysis we evaluated the prevalence and the clinical<br />
spectrum of primary cutaneous lymphomas (PCL) diagnosed and treated at the<br />
Department of Dermatology in St. Pölten, Lower Austria, between 2006 and <strong>2012</strong>. The<br />
Department is a dermatology referral center providing secondary and tertiary care for<br />
a population of about 600,000.<br />
Methods: Pathology reports electronically archieved between 2006 and <strong>2012</strong> were<br />
screened for the terms lymphoma, mycosis fungoides and lymphomatoid papulosis.<br />
The resulting patient list was manually checked for errors and duplicates, verified and<br />
correlated with patient records and history.<br />
Results: We identified 56 patients (17 females and 39 males) with ages at diagnosis<br />
ranging from 13 to 85 yrs and a median of 58 yrs. 43 pts (77%) had cutaneous T-cell<br />
lymphomas (CTCL) and 13 pts (23%) had cutaneous B-cell lymphomas (CBCL). 33<br />
patients were classified as mycosis fungoides (MF; stages: IA n=17, IB n=5, IIA n=2, IIB<br />
n=8, III n=1). Large cell transformation was observed in 3 pts. Among pts with CTCL<br />
other diagnoses were Sezary syndrome (n=2), lymphomatoid papulosis (n=6), CD4+<br />
small/medium seized pleomorphic T-cell lymphoma (n=1), and subcutaneous<br />
panniculitis-like T-cell lymphoma (n=1). CBCL was classified as follicle center lymphoma<br />
in 6 patients, marginal zone lymphoma in 4 patients, and diffuse large B-cell lymphoma,<br />
leg type, in 3 patients.<br />
Conclusion: Our data correspond well with the published annual incidence of PCL<br />
(0.5-1 per 100,000) and with the published distribution of separate disease entities. In<br />
conclusion, for sufficiently large populations it appears reasonable to provide<br />
specialized care for pts with PCL at centers with expertise in dermato-oncology.<br />
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