11.12.2012 Aufrufe

PROGRAMM JAHRESTAGUNG 2012 30. Nov. – 2. Dez ... - ÖGDV

PROGRAMM JAHRESTAGUNG 2012 30. Nov. – 2. Dez ... - ÖGDV

PROGRAMM JAHRESTAGUNG 2012 30. Nov. – 2. Dez ... - ÖGDV

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Poster Tumore der Haut<br />

P 45<br />

The Prevalence of Primary Cutaneous Lymphomas at a Dermatology Referral<br />

Center in Lower Austria<br />

Andrea Kern 1<br />

Johanna Eder 1,2<br />

Melitta Kitzwoegerer 3<br />

Roland Sedivy 3<br />

Franz Trautinger 1,2<br />

1 Landesklinikum St. Pölten, Karl Landsteiner Institut für Dermatologische Forschung,<br />

Propst-Führer-Straße 4, A-3100 St. Pölten<br />

2 Landesklinikum St. Pölten, Abteilung für Haut- und Geschlechtskrankheiten,<br />

Propst-Föhrer-Straße 4, A-3100 St. Pülten<br />

3 Landesklinikum St. Pölten, Institut für klinische Pathologie,<br />

Propst-Führer-Straße 4, A-3100 St. Pölten<br />

Introduction: In this retrospective analysis we evaluated the prevalence and the clinical<br />

spectrum of primary cutaneous lymphomas (PCL) diagnosed and treated at the<br />

Department of Dermatology in St. Pölten, Lower Austria, between 2006 and <strong>2012</strong>. The<br />

Department is a dermatology referral center providing secondary and tertiary care for<br />

a population of about 600,000.<br />

Methods: Pathology reports electronically archieved between 2006 and <strong>2012</strong> were<br />

screened for the terms lymphoma, mycosis fungoides and lymphomatoid papulosis.<br />

The resulting patient list was manually checked for errors and duplicates, verified and<br />

correlated with patient records and history.<br />

Results: We identified 56 patients (17 females and 39 males) with ages at diagnosis<br />

ranging from 13 to 85 yrs and a median of 58 yrs. 43 pts (77%) had cutaneous T-cell<br />

lymphomas (CTCL) and 13 pts (23%) had cutaneous B-cell lymphomas (CBCL). 33<br />

patients were classified as mycosis fungoides (MF; stages: IA n=17, IB n=5, IIA n=2, IIB<br />

n=8, III n=1). Large cell transformation was observed in 3 pts. Among pts with CTCL<br />

other diagnoses were Sezary syndrome (n=2), lymphomatoid papulosis (n=6), CD4+<br />

small/medium seized pleomorphic T-cell lymphoma (n=1), and subcutaneous<br />

panniculitis-like T-cell lymphoma (n=1). CBCL was classified as follicle center lymphoma<br />

in 6 patients, marginal zone lymphoma in 4 patients, and diffuse large B-cell lymphoma,<br />

leg type, in 3 patients.<br />

Conclusion: Our data correspond well with the published annual incidence of PCL<br />

(0.5-1 per 100,000) and with the published distribution of separate disease entities. In<br />

conclusion, for sufficiently large populations it appears reasonable to provide<br />

specialized care for pts with PCL at centers with expertise in dermato-oncology.<br />

101

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