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HerzSupplement - Pentalong von Actavis

HerzSupplement - Pentalong von Actavis

HerzSupplement - Pentalong von Actavis

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we speculate that GTN affects ROS formation<br />

more than other nitrates due to its<br />

strong inhibitory effect on ALDH2­dehydrogenase<br />

activity.<br />

Keywords: organic nitrates – reactive oxygen<br />

species – dihydrorhodamine 123 –<br />

mitochondrial aldehyde dehydrogenase<br />

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Für die Verfasser:<br />

Dr. Tim Bauer<br />

Uniklinik Köln, Institut für Pharmakologie<br />

Gleueler Straße 24<br />

50931 Köln, Germany<br />

Tel.: +49 (0) 221 4786038<br />

Fax: +49 (0) 221 4785022<br />

E-Mail: tim.bauer@uk-koeln.de<br />

Organische Nitrate<br />

55

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