TiHo Bibliothek elib - Tierärztliche Hochschule Hannover

LITERATURVERZEICHNIS
LÖSCHER, W., SILLS, G.J., 2007. Drug resistance in epilepsy: why is a simple explanation not
enough? Epilepsia 48: 2370-2372.
LÖSCHER, W., LUNA-TORTOS, C., RÖMERMANN, K., FEDROWITZ, M., 2011. Do ATP-binding
cassette transporters cause pharmacoresistance in epilepsy? Problems and approaches in
determining which antiepileptic drugs are affected. Curr Pharm Des. 17: 2808-2828.
LUNA-TORTÓS, C., FEDROWITZ, M., LÖSCHER, W., 2008: Several major antiepileptic drugs are
substrates for human P-glycoprotein. Neuropharmacology 55: 1364-1375.
LUNA-TORTÓS, C., FEDROWITZ, M., LÖSCHER, W., 2010. Evaluation of transport of common
antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that
are overexpressed in pharmacoresistant epilepsy. Neuropharmacology. 58: 1019-1032.
LUNA-TORTÓS, C., RAMBECK, B., JÜRGENS, U., LÖSCHER, W., 2009. The Antiepileptic Drug
Topiramate is a Substrate for Human P-glycoprotein but Not Multidrug Resistance Proteins.
Pharm. Res. 26: 2464-2470.
LUNDQUIST, S., RENFTEL, M., 2002. The use of in vitro cell culture models for mechanistic studies
and as permeability screens for the blood-brain barrier in the pharmaceutical industry--
background and current status in the drug discovery process. Vascul Pharmacol. 38: 355-64.
LUO, G., CUNNINGHAM, M., KIM, S., BURN, T., LIN, J., SINZ, M., HAMILTON, G., RIZZO, C.,
JOLLEY, S., GILBERT, D., DOWNEY, A., MUDRA, D., GRAHAM, R., CARROLL, K., XIE, J.,
MADAN, A., PARKINSON, A., CHRIST, D., SELLING, B., LECLUYSE, E., GAN, L.S., 2002.
CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay
and CYP3A4 expression in human hepatocytes. Drug Metab. Dispos. 30: 795–804.
MAHAR DOAN, K.M., HUMPHREYS, J.E., WEBSTER, L.O., WRING, S.A., SHAMPINE, L.J.,
SERABJIT-SINGH, C.J., ADKISON, K.K., POLLI, J.W., 2002. Passive permeability and P-
glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS
marketed drugs. J. Pharmacol. Exp. Ther. 303: 1029-1037.
MAINES, L.W., ANTONETTI, D.A., WOLPERT, E.B., SMITH, C.D., 2005. Evaluation of the role of P-
glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine
retinal endothelial cells. Neuropharmacology 49: 610-617.
MARCHI, N., GUISO, G, RIZZI, M., PIRKER, S., NOVAK, K., CZECH, T., BAUMGARTNER, C.,
JANIGRO, D., CACCIA, S., VEZZANI, A., 2005. A pilot study on brain-to-plasma partition of
10,11-dyhydro-10-hydroxy-5Hdibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression
in epilepsy patients not responding to oxcarbazepine. Epilepsia 46: 1613-1619.
MARCHI, N., HALLENE, K.L., KIGHT, K.M., CUCULLO, L., MODDEL, G., BINGAMAN, W., DINI, G.,
VEZZANI, A., JANIGRO, D., 2004. Significance of MDR1 and multiple drug resistance in
refractory human epileptic brain. BMC Med. 2: 37.
MARTIN, P., RILEY, R., BACK, D.J., OWEN, A., 2008. Comparison of the induction profile for drug
disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells.
Br. J. Pharmacol. 153: 805-819.
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