Ressortforschungsberichte zur kerntechnischen Sicherheit und zum ...

Reference:
First author (year)
Area of
study
Type of study Diagnosis of patients treated
with ionising radiation
Deeg et al., 1984 USA Cohort study BMT in haematological
malignancy and aplastic
anaemia
Benign diseases
Hall et al., 1999 Sweden Cohort study Skin haemangioma patients
treated in childhood
Chmelevsky et al.,
1988 and similar
Stefani et al., 1989
Number
irradiated
patients
n=181
irradiated
patients
n=484
exposed
Control group definition Number nonirradiated
controls
Same diagnosis, chemotherapeutically
conditioned
patients
Same diagnosis, but nonirradiated
– 115 –
Recruitment
period
Follow-up
period
Type of ionising radiation
applied in irradiated group
(as given in the paper)
n=96 1969-1981 1-12 years TBI with two opposing 60-Co
sources
n=89 1920-1959 1993-1994 X-ray, flat radium (226)
containers, radium needles and
tubes
Germany Cohort study TB/ankylosing spondylitis n=831 - - 1945-1952 Follow-up
through
1986
Repeated i.v.-injections of
Radium 224
(short-lived α-emitter)
TBI: total body irradiation; s-TBI: single dose TBI application; f-TBI: fractionated TBI application; TBD: total body dose; LD: lens dose; RCT: randomized controlled trial;
GVHD: Graft-versus-host disease; SCT: Stem-cell transplantation, BMT: Bone marrow transplantation; ECI: estimated cataract incidence; LOCS: lens opacification classification
system; TSR: transscleral resection; IBT: I-125 brachytherapy ; XRT: X-ray treatment; 95% CI: 95% confidence interval