Solubilisierung stark lipophiler Arzneistoffe in lipidhaltige ...

Solubilisierung stark lipophiler Arzneistoffe in lipidhaltige ... Solubilisierung stark lipophiler Arzneistoffe in lipidhaltige ...

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Literaturverzeichnis 181. Feldman, S. und Gibaldi, M., Physiologic surface-active agents and drug absorption. I. Effect of sodium taurodeoxycholate on salicylate transfer across the everted rat intestine, J. Pharm. Sci. 58 (1969) 425-431. 182. Alhaique, F., Giacchetti, D., Marchetti, M., und Riccieri, F. M., Effect of a second solubilizate on the partition coefficient of drugs in micellar solution and their permeation rate across an artificial membrane, J. Pharm. Pharmacol. 29 (1977) 401-406. 183. De Castro, B., Gameiro, P., Guimaraes, C., Lima, J. L. F. C., und Reis, S., Partition coefficients of beta-blockers in bile salt/lecithin micelles as a tool to assess the role of mixed micelles in gastrointestinal absorption, Biophysical Chemistry 90 (2001) 31-43. 184. De Castro, B., Gameiro, P., Guimaraes, C., Lima, J. L. F. C., und Reis, S., Study of partition of nitrazepam in bile salt micelles and the role of lecithin, J. Pharm. Biomed. Anal. 24 (2001) 595- 602. 185. Poelma, F. G. J., Breaes, R., und Tukker, J. J., Intestinal absorption of drugs . ΙΙΙ. The influence of taurocholate on the disappearance kinetics of hydrophilic and lipophilic drugs from the small intestine of the rat, Pharm. Res. 7 (1990) 392-397. 186. Lichtenberger, L. M., The hydrophobic barrier properties of gastrointestinal mucus, Annu. Rev. Physiol. 57 (1995) 565-583. 187. Larhed, A. W., Artursson, P., Grasjo, J., und Bjork, E., Diffusion of drugs in native and purified gastrointestinal mucus, J. Pharm. Sci. 86 (1997) 660-665. 188. Muranishi, S., Muranushi, N., und Sezaki, H., Improvement of absolute bioavailability of normally poorly absorbed drugs: inducment of the intestinal absorption of streptomycin and gentamycin by lipid-bile salt mixed micelles in rat and rabbit, Int. J. Pharm. 2 (1979) 101-111. 189. Grisafe, J. A. und Hayton, W. L., Effects of short and medium chain fatty acids on absorption of lipophilic drugs from perfused rat intestine, J. Pharm. Sci. 67 (1978) 1211-1215. 190. Meaney, C. und O'Driscoll, C., Mucus as a barrier to the permeability of hydrophilic and lipophilic compounds in the absence and presence of sodium taurocholate micellar systems using cell culture models, Eur. J. Pharm. Sci. 8 (1999) 167-175. 191. Muranushi, N., Kunugawa, M., Nakajima, Y., Muranishi, S., und Sezaki, H., Mechanism for the inducment of the intestinal absorption of poorly absorbed drugs by mixed micelles Ι. Effects of various lipid-bile salt mixed micelles on the intestinal absorption of streptomycin in rat, Int. J. Pharm. 4 (1980) 271-279. 192. Fagerholm, U., Sjostrom, B., Sroka-Markovic, J., Wijk, A., Svensson, M., und Lennernäs, H., The effect of a drug-delivery system consisting of soybean phosphatidyl choline and medium-chain monoacylglycerol on the intestinal permeability of hexarelin in the rat, J. Pharm. Pharmacol. 50 (1998) 467-473. 193. Ganem-Quintanar, A., Quintanar-Guerrero, D., und Buri, P., Monoolein: A review of the pharmaceutical applications, Drug Dev. Ind. Pharm. 26 (2000) 809-820. 194. Muranushi, N., Nakajima, M., Kinugawa, M., Muranishi, S., und Sezaki, H., Mechanism for the inducement of the intestinal absorption of poorly absorbed drugs by mixed micelles ΙΙ. Effect of the incorporation of various lipids on the permeability of liposomal membranes, Int. J. Pharm. 4 (1980) 281-290. 195. Perry, E. A., Chandler, S. G., und Ferdinando, J. J. C., Oral pharmaceutical compositions containing sex hormones, Patent: WO 9740823, (1996). 196. Tengamnuay, P. und Mitra, A. K., Bile salt-fatty acid mixed micelles as nasal absorption promoters of peptides. I. Effects of ionic strength, adjuvant composition, and lipid structure on the nasal absorption of [D-Arg2]kyotorphin, Pharm. Res. 7 (1990) 127-133. 197. Yeh, P. Y., Effect of Medium-Chain Glycerides on Physiological Properties of Rabbit Intestinal Epithelium in Vitro, Pharm. Res. 11 (1994) 1148-1154. 198. Yu, L. X. und Amidon, G. L., Analytical Solutions to Mass Transfer, In: Amidon, G. L., Lee, P. I., und Topp, E. M. [Hrsg.], Transport Processes in Pharmaceutical Systems, Marcel Dekker, Inc., NY, USA, (2000), S. 23-53. cxviii

Literaturverzeichnis 199. Riegelman, S., Allawala, N. A., Hrenoff, M. K., und Strait, L. A., The ultraviolet absorption spectrum as a criterion of the type of solubilization, J. Colloid Sci. 13 (1958) 208-217. 200. Guttman, D. E., Hamlin, W. E., Shell, J. W., und Wagner, J. G., Solubilization of antiinflammatory steroids by aqueous solutions of Triton WR-1339, J. Pharm. Sci. 50 (1961) 305- 307. 201. Kosower, E. M., The Effect of Solvent on Spectra. Ι. A new Empirical Measure of Solvent Polarity: Z-Values, J. Am. Chem. Soc. 80 (1958) 3253-3260. 202. Kosower, E. M., The Effect of Solvent on Spectra. ΙΙ. Correlation of Spectral Absorption Data with Z-Values, J. Am. Chem. Soc. 80 (1958) 3261-3267. 203. Kosower, E. M., The Effect of Solvent on Spectra. ΙΙΙ. The Use of Z-Values in Connection with Kinetic Data, J. Am. Chem. Soc. 80 (1958) 3267-3270. 204. Kosower, E. M. und Wu, G.-S., The Effect of Solvent on Spectra. V. The Low Intensity (n to π*) Electronic Transition of Cyclic Ketones, J. Am. Chem. Soc. 83 (1961) 3142-3147. 205. Kosower, E. M., Wu, G.-S., und Sorensen, T. S., Effect of Solvent on Spectra. VI Detection of Solvent Effect on Molecular Conformation or Shape through Z-Values, J. Am. Chem. Soc. 83 (1961) 3147. 206. IUPAC, Z-value (def.), IUPAC Compendium of Chemical Terminology, 2 nd Edn., (1997), http://www.iupac.org/goldbook/Z06737.pdf. 207. IUPAC, Cybotactic Region (def.), IUPAC Compendium of Chemical Terminology, 2 nd Edn., (1997), http://www.iupac.org/goldbook/C01490.pdf. 208. Bjaastad, S. G. und Hall, N. A., Preliminary investigation of the Z-value measure of relative solvent polarity in micellar solubilization, J. Pharm. Sci. 56 (1967) 504-507. 209. Thakkar, A. L. und Hall, N. A., Micellar solubilization of testosterone. I. In aqueous solutions of polysorbates, J. Pharm. Sci. 56 (1967) 1121-1125. 210. Thakkar, A. L. und Hall, N. A., Micellar solubilization of testosterone. II. In aqueous solutions of some ionic surfactants, J. Pharm. Sci. 57 (1968) 1394-1398. 211. Janich, M., Licht- und Neutronenstreuexperimente an Gallensalzmizellen, Diss., Martin-Luther- Universität Halle-Wittenberg, DE, (1998). 212. Provencher, S. W., A constrained regularization method for inverting data represented by linear algebraic or integral equations, Comput. Phys. Commun. 27 (1982) 213-227. 213. Johnsen, R. und Brown, W., An overview of current methods of analyzing QLS data, In: Harding, S. E., Sattelle, D. B., und Bloomfield, V. A. [Hrsg.], LASER Light Scattering in Biochemistry, Royal Society of Chemistry, Cambridge, UK, (1992), S. 77-91. 214. Johnsen, R. und Brown, W., An investigation of rigid rod-like particles in dilute solution, In: Harding, S. E., Sattelle, D. B., und Bloomfield, V. A. [Hrsg.], LASER Light Scattering in Biochemistry, Royal Society of Chemistry, Cambridge, UK, (1992), S. 161-183. 215. Pecora, R., Dynamic light scattering: applications of photon correlation spectroscopy, Plenum Press, NY, USA, (1985). 216. Berne, B. J. und Pecora, R., Dynamic light scattering: with applications to chemistry, biology, and physics, (Reprint. Originally published: Wiley, NY, 1976), R.E. Krieger Pub. Co, Malabar, Fl, USA, (1990). 217. Maier, D., Ein neues kombiniertes Meß- und Auswerteverfahren für die dynamische Lichtstreuung, Diss., Fakultät der Physik der Albert-Ludwigs-Universität Freiburg, DE, (1996). 218. Shukla, A., Characterization of Microemulsions using Small Angle Scattering Techniques, Diss., Martin-Luther-Universität Halle-Wittenberg, DE, (2003). 219. Substance Description: Phospholipon® 90 H (E-PP90H.DOC/pe), Natterman Phospholipid GmbH, (Aug. 1998). 220. Substance Description: Phospholipon® 90/90G (E-PL90.DOC/br), Natterman Phospholipid GmbH, (Mar. 1996). cxix

Literaturverzeichnis<br />

181. Feldman, S. und Gibaldi, M., Physiologic surface-active agents and drug absorption. I. Effect of<br />

sodium taurodeoxycholate on salicylate transfer across the everted rat <strong>in</strong>test<strong>in</strong>e, J. Pharm. Sci. 58<br />

(1969) 425-431.<br />

182. Alhaique, F., Giacchetti, D., Marchetti, M., und Riccieri, F. M., Effect of a second solubilizate on<br />

the partition coefficient of drugs <strong>in</strong> micellar solution and their permeation rate across an artificial<br />

membrane, J. Pharm. Pharmacol. 29 (1977) 401-406.<br />

183. De Castro, B., Gameiro, P., Guimaraes, C., Lima, J. L. F. C., und Reis, S., Partition coefficients of<br />

beta-blockers <strong>in</strong> bile salt/lecith<strong>in</strong> micelles as a tool to assess the role of mixed micelles <strong>in</strong><br />

gastro<strong>in</strong>test<strong>in</strong>al absorption, Biophysical Chemistry 90 (2001) 31-43.<br />

184. De Castro, B., Gameiro, P., Guimaraes, C., Lima, J. L. F. C., und Reis, S., Study of partition of<br />

nitrazepam <strong>in</strong> bile salt micelles and the role of lecith<strong>in</strong>, J. Pharm. Biomed. Anal. 24 (2001) 595-<br />

602.<br />

185. Poelma, F. G. J., Breaes, R., und Tukker, J. J., Intest<strong>in</strong>al absorption of drugs . ΙΙΙ. The <strong>in</strong>fluence<br />

of taurocholate on the disappearance k<strong>in</strong>etics of hydrophilic and lipophilic drugs from the small<br />

<strong>in</strong>test<strong>in</strong>e of the rat, Pharm. Res. 7 (1990) 392-397.<br />

186. Lichtenberger, L. M., The hydrophobic barrier properties of gastro<strong>in</strong>test<strong>in</strong>al mucus, Annu. Rev.<br />

Physiol. 57 (1995) 565-583.<br />

187. Larhed, A. W., Artursson, P., Grasjo, J., und Bjork, E., Diffusion of drugs <strong>in</strong> native and purified<br />

gastro<strong>in</strong>test<strong>in</strong>al mucus, J. Pharm. Sci. 86 (1997) 660-665.<br />

188. Muranishi, S., Muranushi, N., und Sezaki, H., Improvement of absolute bioavailability of normally<br />

poorly absorbed drugs: <strong>in</strong>ducment of the <strong>in</strong>test<strong>in</strong>al absorption of streptomyc<strong>in</strong> and gentamyc<strong>in</strong> by<br />

lipid-bile salt mixed micelles <strong>in</strong> rat and rabbit, Int. J. Pharm. 2 (1979) 101-111.<br />

189. Grisafe, J. A. und Hayton, W. L., Effects of short and medium cha<strong>in</strong> fatty acids on absorption of<br />

lipophilic drugs from perfused rat <strong>in</strong>test<strong>in</strong>e, J. Pharm. Sci. 67 (1978) 1211-1215.<br />

190. Meaney, C. und O'Driscoll, C., Mucus as a barrier to the permeability of hydrophilic and lipophilic<br />

compounds <strong>in</strong> the absence and presence of sodium taurocholate micellar systems us<strong>in</strong>g cell<br />

culture models, Eur. J. Pharm. Sci. 8 (1999) 167-175.<br />

191. Muranushi, N., Kunugawa, M., Nakajima, Y., Muranishi, S., und Sezaki, H., Mechanism for the<br />

<strong>in</strong>ducment of the <strong>in</strong>test<strong>in</strong>al absorption of poorly absorbed drugs by mixed micelles Ι. Effects of<br />

various lipid-bile salt mixed micelles on the <strong>in</strong>test<strong>in</strong>al absorption of streptomyc<strong>in</strong> <strong>in</strong> rat, Int. J.<br />

Pharm. 4 (1980) 271-279.<br />

192. Fagerholm, U., Sjostrom, B., Sroka-Markovic, J., Wijk, A., Svensson, M., und Lennernäs, H., The<br />

effect of a drug-delivery system consist<strong>in</strong>g of soybean phosphatidyl chol<strong>in</strong>e and medium-cha<strong>in</strong><br />

monoacylglycerol on the <strong>in</strong>test<strong>in</strong>al permeability of hexarel<strong>in</strong> <strong>in</strong> the rat, J. Pharm. Pharmacol. 50<br />

(1998) 467-473.<br />

193. Ganem-Qu<strong>in</strong>tanar, A., Qu<strong>in</strong>tanar-Guerrero, D., und Buri, P., Monoole<strong>in</strong>: A review of the<br />

pharmaceutical applications, Drug Dev. Ind. Pharm. 26 (2000) 809-820.<br />

194. Muranushi, N., Nakajima, M., K<strong>in</strong>ugawa, M., Muranishi, S., und Sezaki, H., Mechanism for the<br />

<strong>in</strong>ducement of the <strong>in</strong>test<strong>in</strong>al absorption of poorly absorbed drugs by mixed micelles ΙΙ. Effect of<br />

the <strong>in</strong>corporation of various lipids on the permeability of liposomal membranes, Int. J. Pharm. 4<br />

(1980) 281-290.<br />

195. Perry, E. A., Chandler, S. G., und Ferd<strong>in</strong>ando, J. J. C., Oral pharmaceutical compositions<br />

conta<strong>in</strong><strong>in</strong>g sex hormones, Patent: WO 9740823, (1996).<br />

196. Tengamnuay, P. und Mitra, A. K., Bile salt-fatty acid mixed micelles as nasal absorption<br />

promoters of peptides. I. Effects of ionic strength, adjuvant composition, and lipid structure on<br />

the nasal absorption of [D-Arg2]kyotorph<strong>in</strong>, Pharm. Res. 7 (1990) 127-133.<br />

197. Yeh, P. Y., Effect of Medium-Cha<strong>in</strong> Glycerides on Physiological Properties of Rabbit Intest<strong>in</strong>al<br />

Epithelium <strong>in</strong> Vitro, Pharm. Res. 11 (1994) 1148-1154.<br />

198. Yu, L. X. und Amidon, G. L., Analytical Solutions to Mass Transfer, In: Amidon, G. L., Lee, P. I.,<br />

und Topp, E. M. [Hrsg.], Transport Processes <strong>in</strong> Pharmaceutical Systems, Marcel Dekker, Inc.,<br />

NY, USA, (2000), S. 23-53.<br />

cxviii

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