Solubilisierung stark lipophiler Arzneistoffe in lipidhaltige ...

Solubilisierung stark lipophiler Arzneistoffe in lipidhaltige ... Solubilisierung stark lipophiler Arzneistoffe in lipidhaltige ...

23.10.2012 Aufrufe

Literaturverzeichnis 141. Brzezowska, E., Dmochowska-Gladysz, J., Kolek, T., und Nobilec, E., Biotransformation--XXXIV. Metabolism of testosterone esters in fungi cultures, J. Steroid Biochem. Mol. Biol. 46 (1993) 259-263. 142. Hobbelen, P. M., Coert, A., und Geelen, J. A., Interactions of steroids with serum lipoproteins, Biochem. Pharmacol. 24 (1975) 165-172. 143. Heller, R. F., Wheeler, M. J., Micallef, J., Miller, N. E., und Lewis, B., Relationship of high density lipoprotein cholesterol with total and free testosterone and sex hormone binding globulin, Acta Endocrinol. 104 (1983) 253-256. 144. Pardridge, W. M., Serum bioavailability of sex steroid hormones., Clin. Endocrinol. Metab. 15 (1986) 259-278. 145. Petra, P. H., Stanczyk, F. Z., Namkung, P. C., Fritz, M. A., und Novy, M. J., Direct effect of sex steroid-binding protein (SBP) of plasma on the metabolic clearance rate of testosterone in the rhesus macaque, J. Steroid Biochem. 22 (1985) 739-746. 146. Westphal, U., Characteristics of steroid-protein interactions, including results on a progesteronebinding globulin., In: James, V. H. T. und Martini, L. [Hrsg.], Horm.Steroids: Proc. Int. Congr., International congress series, Excerpta Medica Foundation, Amsterdam, Neth., (1971), S. 410- 419. 147. Westphal, U., Protein binding of steroid hormones, Klin. Wochenschr. 55 (1977) 877-880. 148. Tax, L., Absolute bioavailability of testosterone after oral administration of testosteroneundecanoate and testosterone. Letters to the Editor, Eur. J. Drug Metab. Pharmacokinet. 12 (1987) 226. 149. Grisafe, J. A. und Hayton, W. L., Intestinal absorption of griseofulvin from a triolein digestion mixture in rats, J. Pharm. Sci. 67 (1978) 895-899. 150. Hoffman, N. E., The relationship between uptake in-vitro of oleic acid and micellar solubilization, Biochim. Biophys. Acta 196 (1970) 193-203. 151. Poelma, F. G. J., Breas, R., Tukker, J. J., und Crommelin, D. J. A., Intestinal absorption of drugs. The influence of mixed micelles on the disappearance kinetics of drugs from the small intestine of the rat, J. Pharm. Pharmacol. 43 (1991) 317-324. 152. Wiedmann, T. S., Deye, C., und Kallick, D., Interaction of bile salt and phospholipids with bovine submaxillary mucin, Pharm. Res. 18 (2001) 45-53. 153. Wilson, F. A. und Dietschy, J. M., Characterization of bile acid absorption across the unstirred water layer and brush border of the rat jejunum, J. Clin. Invest. 51 (1972) 3015-3025. 154. Westergaard, H. und Dietschy, J. M., The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell, J. Clin. Invest. 58 (1976) 97- 108. 155. Lindström, M., Intestinal Lipid Absorption with Emphasis on Non-polar Lipids and on the Importance of Non-micellar Aggregates of Bile Salts and lipolytic Products, Diss., Department of Medical and Physiological Chemistry, University of Lund, Sweden, (1988). 156. Li, C. Y., Zimmerman, C. L., und Wiedmann, T. S., Diffusivity of bile salt/phospholipid aggregates in mucin, Pharm. Res. 13 (1996) 535-541. 157. Martin, G. P., Marriott, C., und Kellaway, I. W., Direct effect of bile salts and phospholipids on the physical properties of mucus, Gut 19 (1978) 103-107. 158. Poelma, F. G. J., Breas, R., und Tukker, J. J., Intestinal absorption of drugs. IV. The influence of taurocholate and L-cysteine on the barrier function of mucus , Int. J. Pharm. 64 (1990) 161-169. 159. Meaney, C. M. und O'Driscoll, C. M., A comparison of the permeation enhancement potential of simple bile salt and mixed bile salt:fatty acid micellar systems using the CaCo-2 cell culture model, Int. J. Pharm. 207 (2000) 21-30. 160. Schreier, S., Malheiros, S. V. P., und De Paula, E., Surface active drugs: self-association and interaction with membranes and surfactants. Physicochemical and biological aspects, Biochim. Biophys. Acta-Biomembranes 1508 (2000) 210-234. cxvi

Literaturverzeichnis 161. Segura-Bono, M. J., Garrigues, T. M., Merino, V., und Bermejo, M. V., Compared effects of synthetic and natural bile acid surfactants on xenobiotic absorption. III. studies with mixed micelles, Int. J. Pharm. 107 (1994) 159-166. 162. Rege, B., Kao, J., und Polli, J., Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers, Eur. J. Pharm. Sci. 16 (2002) 237. 163. Jelinek, A., In-vitro-Toxizität grenzflächenaktiver Substanzen: Wirkung auf Zellmembran, mitochondriale Funktion und Apoptose, Diss., Martin-Luther-Universität Halle-Wittenberg, DE, (2001). 164. Taylor, C. B., The effect of cetyltrimethylammonium bromide and some related compounds on transport and metabolism in the intestine of the rat in vitro, J. Physiol. 165 (1963) 199-218. 165. Alhaique, F., Marchetti, M., Riccieri, F. M., und Santucci, E., A negative cooperative binding process between chloramphenicol and sodium dodecyl sulfate to bovine serum albumin: a possible effect on drug absorption, Experientia 31 (1975) 215-218. 166. Warisnoicharoen, W., Lansley, A. B., und Lawrence, M. J., Toxicological evaluation of mixtures of nonionic surfactants, alone and in combination with oil, J. Pharm. Sci. 92 (2003) 859-868. 167. Charman, W. N. und Stella, V. J., Transport of lipophilic molecules by the intestinal lymphatic system, Adv. Drug Deliv. Rev. 7 (1991) 1-14. 168. Charman, W. N., Lipid vehicle and formulation effects on intestinal lymphatic drug transport, In: Charman, W. N. und Stella, V. J. [Hrsg.], Lymphatic Transport of Drugs, CRC Press, Boca Raton, FL, USA, (1992), S. 113-179. 169. Anderberg, E. K., lindmark, T., und Artursson, P., Sodium Caprate elicits Dilatations in Human Intestinal Tight Junctions and Enhances Drug Absorption by the Paracellular Route, Pharm. Res. 10 (1993) 857-864. 170. Ward, P. D., Tippin, T. K., und Thakker, D. R., Enhancing paracellular permeability by modulating epithelial tight junctions, Pharm. Sci. Technol. Today 3 (2000) 346-358. 171. Oberle, R. L., Moore, T. J., und Krummel, D. A., Evaluation of mucosal damage of surfactants in rat jejunum and colon, J. Pharmacol. Toxicol. Methods 33 (1995) 75-81. 172. Lapré, J. A., Termont, D. S. M. L., Groen, A. K., und van der Meer, R., Lytic effects of mixed micelles of fatty acids and bile acids, Am. J. Physiol. 263 (1992) G333-G337. 173. Martin, G. P., El-Hariri, L., und Marriott, C., Bile Salt- and Lysophosphatidilylcholine-induced Membrane Damage in Human Erythrocytes, J. Pharm. Pharmacol. 44 (1992) 646-650. 174. Kraus, C., Mehnert, W., und Froemming, K., Hemolytic activity of mixed micellar solutions of Solutol HS 15 and sodium deoxycholate, Acta Pharm. Technol. 36 (1990) 221-225. 175. Grant, R. L., Yao, C., Gabaldon, D., und Acosta, D., Evaluation of surfactant cytotoxicity potential by primary cultures of ocular tissues: I. Characterization of rabbit corneal epithelial cells and initial injury and delayed toxicity studies, Toxicology 76 (1992) 153-176. 176. Effendy, I. und Maibach, H. I., Surfactants and experimental irritant contact dermatitis, Contact Dermatitis 33 (1995) 217-225. 177. Feldman, S., Reinhard, M., und Willson, C., Effect of sodium taurodeoxycholate on biological membranes: release of phosphorus, phospholipid, and protein from everted rat small intestine, J. Pharm. Sci. 62 (1973) 1961-1964. 178. Whitmore, D. A., Brookes, L. G., und Wheeler, K. P., Relative effects of different surfactants on intestinal absorption and the release of proteins and phospholipids from the tissue, J. Pharm. Pharmacol. 31 (1979) 277-283. 179. Gullikson, G. W., Cline, W. S., Lorenzsonn, V., Benz, L., Olsen, W. A., und Bass, P., Effects of anionic surfactants on hamster small intestinal membrane structure and function: relationship to surface activity, Gastroenterology 73 (1977) 501-511. 180. Coleman, R., Lowe, P. J., und Billington, D., Membrane lipid composition and susceptibility to bile salt damage, Biochim. Biophys. Acta 599 (1980) 294-300. cxvii

Literaturverzeichnis<br />

161. Segura-Bono, M. J., Garrigues, T. M., Mer<strong>in</strong>o, V., und Bermejo, M. V., Compared effects of<br />

synthetic and natural bile acid surfactants on xenobiotic absorption. III. studies with mixed<br />

micelles, Int. J. Pharm. 107 (1994) 159-166.<br />

162. Rege, B., Kao, J., und Polli, J., Effects of nonionic surfactants on membrane transporters <strong>in</strong><br />

Caco-2 cell monolayers, Eur. J. Pharm. Sci. 16 (2002) 237.<br />

163. Jel<strong>in</strong>ek, A., In-vitro-Toxizität grenzflächenaktiver Substanzen: Wirkung auf Zellmembran,<br />

mitochondriale Funktion und Apoptose, Diss., Mart<strong>in</strong>-Luther-Universität Halle-Wittenberg, DE,<br />

(2001).<br />

164. Taylor, C. B., The effect of cetyltrimethylammonium bromide and some related compounds on<br />

transport and metabolism <strong>in</strong> the <strong>in</strong>test<strong>in</strong>e of the rat <strong>in</strong> vitro, J. Physiol. 165 (1963) 199-218.<br />

165. Alhaique, F., Marchetti, M., Riccieri, F. M., und Santucci, E., A negative cooperative b<strong>in</strong>d<strong>in</strong>g<br />

process between chloramphenicol and sodium dodecyl sulfate to bov<strong>in</strong>e serum album<strong>in</strong>: a<br />

possible effect on drug absorption, Experientia 31 (1975) 215-218.<br />

166. Warisnoicharoen, W., Lansley, A. B., und Lawrence, M. J., Toxicological evaluation of mixtures of<br />

nonionic surfactants, alone and <strong>in</strong> comb<strong>in</strong>ation with oil, J. Pharm. Sci. 92 (2003) 859-868.<br />

167. Charman, W. N. und Stella, V. J., Transport of lipophilic molecules by the <strong>in</strong>test<strong>in</strong>al lymphatic<br />

system, Adv. Drug Deliv. Rev. 7 (1991) 1-14.<br />

168. Charman, W. N., Lipid vehicle and formulation effects on <strong>in</strong>test<strong>in</strong>al lymphatic drug transport, In:<br />

Charman, W. N. und Stella, V. J. [Hrsg.], Lymphatic Transport of Drugs, CRC Press, Boca Raton,<br />

FL, USA, (1992), S. 113-179.<br />

169. Anderberg, E. K., l<strong>in</strong>dmark, T., und Artursson, P., Sodium Caprate elicits Dilatations <strong>in</strong> Human<br />

Intest<strong>in</strong>al Tight Junctions and Enhances Drug Absorption by the Paracellular Route, Pharm. Res.<br />

10 (1993) 857-864.<br />

170. Ward, P. D., Tipp<strong>in</strong>, T. K., und Thakker, D. R., Enhanc<strong>in</strong>g paracellular permeability by modulat<strong>in</strong>g<br />

epithelial tight junctions, Pharm. Sci. Technol. Today 3 (2000) 346-358.<br />

171. Oberle, R. L., Moore, T. J., und Krummel, D. A., Evaluation of mucosal damage of surfactants <strong>in</strong><br />

rat jejunum and colon, J. Pharmacol. Toxicol. Methods 33 (1995) 75-81.<br />

172. Lapré, J. A., Termont, D. S. M. L., Groen, A. K., und van der Meer, R., Lytic effects of mixed<br />

micelles of fatty acids and bile acids, Am. J. Physiol. 263 (1992) G333-G337.<br />

173. Mart<strong>in</strong>, G. P., El-Hariri, L., und Marriott, C., Bile Salt- and Lysophosphatidilylchol<strong>in</strong>e-<strong>in</strong>duced<br />

Membrane Damage <strong>in</strong> Human Erythrocytes, J. Pharm. Pharmacol. 44 (1992) 646-650.<br />

174. Kraus, C., Mehnert, W., und Froemm<strong>in</strong>g, K., Hemolytic activity of mixed micellar solutions of<br />

Solutol HS 15 and sodium deoxycholate, Acta Pharm. Technol. 36 (1990) 221-225.<br />

175. Grant, R. L., Yao, C., Gabaldon, D., und Acosta, D., Evaluation of surfactant cytotoxicity potential<br />

by primary cultures of ocular tissues: I. Characterization of rabbit corneal epithelial cells and <strong>in</strong>itial<br />

<strong>in</strong>jury and delayed toxicity studies, Toxicology 76 (1992) 153-176.<br />

176. Effendy, I. und Maibach, H. I., Surfactants and experimental irritant contact dermatitis, Contact<br />

Dermatitis 33 (1995) 217-225.<br />

177. Feldman, S., Re<strong>in</strong>hard, M., und Willson, C., Effect of sodium taurodeoxycholate on biological<br />

membranes: release of phosphorus, phospholipid, and prote<strong>in</strong> from everted rat small <strong>in</strong>test<strong>in</strong>e,<br />

J. Pharm. Sci. 62 (1973) 1961-1964.<br />

178. Whitmore, D. A., Brookes, L. G., und Wheeler, K. P., Relative effects of different surfactants on<br />

<strong>in</strong>test<strong>in</strong>al absorption and the release of prote<strong>in</strong>s and phospholipids from the tissue, J. Pharm.<br />

Pharmacol. 31 (1979) 277-283.<br />

179. Gullikson, G. W., Cl<strong>in</strong>e, W. S., Lorenzsonn, V., Benz, L., Olsen, W. A., und Bass, P., Effects of<br />

anionic surfactants on hamster small <strong>in</strong>test<strong>in</strong>al membrane structure and function: relationship to<br />

surface activity, Gastroenterology 73 (1977) 501-511.<br />

180. Coleman, R., Lowe, P. J., und Bill<strong>in</strong>gton, D., Membrane lipid composition and susceptibility to<br />

bile salt damage, Biochim. Biophys. Acta 599 (1980) 294-300.<br />

cxvii

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