Matematisk Model for Mavesækkens Tømning - Danmarks Tekniske ...
Matematisk Model for Mavesækkens Tømning - Danmarks Tekniske ...
Matematisk Model for Mavesækkens Tømning - Danmarks Tekniske ...
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68 Simulering af <strong>for</strong>søgsscenarie<br />
Symbol Value Unit<br />
Transfer rate k12 0.066 1/min<br />
Deactivation rate ka1 0.006 1/min<br />
Deactivation rate ka2 0.06 1/min<br />
Deactivation rate ka3 0.03 1/min<br />
Insulin elimination rate ke 0.138 1/min<br />
CHO absorption constant τD 40 min<br />
Insulin absorption constant τS 55 min<br />
CHO utilization AG 0.8 -<br />
Transport insulin sensitivity SI,1 51.2 · 10−4 L/mU<br />
Disposal insulin sensitivity SI,2 8.2 · 10−4 L/mU<br />
EGP insulin sensitivity SI,3 520 · 10−4 L/mU<br />
Insulin distribution volume<br />
Glucose distribution volume<br />
Liver glucose production<br />
VI<br />
BW<br />
VG<br />
BW<br />
EGP0<br />
BW<br />
0.12<br />
0.16<br />
0.0161<br />
L/kg<br />
L/kg<br />
mmol<br />
min /kg<br />
CNS glucose consumption<br />
F01<br />
mmol<br />
BW 0.0097 min /kg<br />
Normalization factor η 6.00 pmol/mU<br />
Transfer rate γ 0.5 1/min<br />
Responsitivity to glucose change K 43.16 mU/mmol<br />
Delay α 0.05 1/min<br />
Responsitivity to glucose<br />
β<br />
BW 0.3303<br />
mU/min<br />
mmol/L /kg<br />
Basal insulin secretion Sb<br />
∗ mU/min<br />
Tabel 6.1: ∗ Parameteren Sb afhænger direkte og indirekte af personens vægt.<br />
Ex <strong>for</strong> BW = 70 kg er Sb = 6.5072 og <strong>for</strong> BW = 60 kg er Sb = 1.8592.
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