Matematisk Model for Mavesækkens Tømning - Danmarks Tekniske ...

More documents

Recommendations

Info

138 LITTERATUR [10] O. Goetze, A. Steingotter, D. Menne, I. R. Van der Voort, M. A. Kwiatek, P. Boesiger, D. Weishaupt, M. Thumshirn, M. Fried, and W. Schwizer. The effect of macronutrients on gastric volume responses and gastric emptying in humans: A magnetic resonance imaging study. Am. J. Physiol., 292:11– 17, 2007. [11] A. C. Guyton and J. E. Hall. Medical Physiology. Elsevier Saunders, 11th edition, 2006. [12] M. Horowitz, D. O’Donovan, K. L. Jones, C. Feinle, C. K. Rayner, and M. Samsom. Gastric emptying in diabetes: Clinical significance and treatment. Diabetic Medicine, 19:177–194, 2002. [13] R. Hovorka, V. Canonico, L. J. Chassin, U. Haueter, M. Massi-Benedetti, M. O. Federici, T. R. Pieber, H. C. Schaller, L. Schaupp, T. Vering, and M. E. Wilinska. Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes. Physiol. Meas., 25:905–920, 2004. [14] R. Hovorka, F. Shojaee-Moradie, P. V. Carroll, L. J. Chassin, I. J. Gowrie, N. C. Jackson, R. S. Tudor, A. M. Umpleby, and R. H. Jones. Partitioning glucose Distribution/Transport, disposal, and endogeneous production during IVGTT. Am J Physiol Endocrinol Metab, 282:E992–E1007, 2002. [15] B. M. Koeppen and B. A. Stanton. Berne and Levy Physiology. Mosby Inc., 6th edition, 2008. [16] F. Levin, T. Edholm, P. T. Schmidt, P. Grybäck, H. Jacobsson, M. Degerblad, C. Höybye, J. J. Holst, J. F. Rehfeld, P. M. Hellström, and E. Näslund. Ghrelin stimulates gastric emptying and hunger in normal-weight humans. J Clin Endocrinol Metab, 91(9):3296–3302, 2006. [17] T. J. Little, A. Russo, M. Horowitz, J. H. Meyer, D. Smyth, K. L. Jones, J. Wishart, M. Bellon, and C. Feinle-Bisset. The effect of free fatty acids on gastric emptying, plasma cholecystokinin (CCK) and peptide YY (PYY), appetite and energy intake in humans are more potent than those of triglycerides. Appetite, 49:308, 2007. [18] J. Ma, C. K. Rayner, K. L. Jones, and M. Horowitz. Diabetic gastroparesis - diagnosis and management. Drugs, 69(8):971–986, 2009. [19] I. L. MacGregor, R. Gueller, H. D. Watts, and J. H. Meyer. The effect of acute hyperglycemia on gastric emptying in man. Gastroenterology, 70(2):190–196, 1976. [20] J. L. Madsen and M. Jensen. Gastrointestinal transit of technetium-99mlabeled cellulose fiber and indium-111-labeled plastic particles. J Nucl Med, 30(3):402–406, 1989.
LITTERATUR 139 [21] C. Dalla Man, M. Camilleri, and C. Cobelli. A system model of oral glucose absorption: Validation on gold standard data. IEEE Trans. Biomed. Eng., 53(12):2472–2478, December 2006. [22] C. Dalla Man, R. A. Rizza, and C. Cobelli. Meal simulation model of the glucose-insulin system. IEEE Trans. Biomed. Eng., 54(10):1740–1749, 2007. [23] N. S. Nair, I. M. Brennan, T. J. Little, D. Gentilcore, T. Hausken, K. L. Jones, J. M. Wishart, M. Horowitz, and C. Feinle-Bisset. Reproducibility of energy intake, gastric emptying, blood glucose, plasma insulin and cholecystokinin responses in healthy young males. Br. J. Nutr., 101:1094–1102, 2009. [24] E. Øster-Jørgensen, S. A. Pedersen, and M. L. Larsen. The influence of induced hyperglycemia on gastric emptying in healthy humans. Scand J Lab Clin Invest, 50:831–836, 1990. [25] R. P. Parker, P. H. S. Smith, and D. M. Taylor. Basic Science of Nuclear Medicine. Churchill Livingstone, 2nd edition, 1984. [26] R. M. Rangayyan. Biomedical Image Analysis. CRC Press, 1st edition, 2005. [27] M. Salehi, T. P Vahl, and D. A. D’Alessio. Regulation of islet hormone release and gastric emptying by endogenous glucagon-like peptide 1 after glucose ingestion. J Clin Endocrinol Metab, 93(12):4909–4916, 2008. [28] T. V. Schroeder, S. Schulze, J. Hilsted, and J. Aldershvile. Basisbog I Medicin Og Kirurgi. Munksgaard Danmark, 3rd edition, 2005. [29] E. Schvarcz, M. Palmér, J. ˚Aman, and C. Berne. Hypoglycemia increases the gastric emptying rate in healthy subjects. Diabetes Care, 18(5):674–676, 1995. [30] E. Schvarcz, M. Palmér, J. ˚Aman, and C. Berne. Accelerated gastric emptying during hypoglycaemia is not associated with changes in plasma motilin levels. Acta Diabetol, 34:194–198, 1997. [31] E. Schvarcz, M. Palmér, J. ˚Aman, B. Lindkvist, and K. W. Beckman. Hypoglycemia increases the gastric emptying in patients with type 1 diabetes mellitus. Diabet. Med., 10:660–663, 1993. [32] R. R. Seeley, T. D. Stephens, and P. Tate. Anatomy and Physiology. McGraw-Hill, 7th edition, 2006. [33] R. E. Teixeira and S. Malin. The next generation of artificial pancreas control algorithms. J. Diabetes Sci. Technol., 2(1):105–112, 2008.
Page 1 and 2:
Matematisk Model for Mavesækkens T
Page 3 and 4:
Abstract The aim of this assignment
Page 5:
Resumé Form˚alet med denne opgave
Page 8 and 9:
vi juni 09 og starten af juli 09. I
Page 10:
viii Tak til Daniel Finan for at ha
Page 13 and 14:
Indhold Abstract i Resumé iii Foro
Page 15 and 16:
Kapitel 1 Introduktion I over 30 ˚
Page 17 and 18:
sygdommen diabetes mellitus samt en
Page 19 and 20:
Kapitel 2 Diabetes Mellitus Det ind
Page 21 and 22:
2.2 Sygdommen diabetes mellitus 7 2
Page 23 and 24:
2.3 Fordøjelsessystemet 9 Figur 2.
Page 25 and 26:
2.3 Fordøjelsessystemet 11 Fra nye
Page 27 and 28:
2.3 Fordøjelsessystemet 13 Figur 2
Page 29 and 30:
2.4 Resume af Kapitel 2 15 forsinke
Page 31 and 32:
Kapitel 3 Nuklear medicin Nuklear m
Page 33 and 34:
3.2 Technetium - 99m og Indium - 11
Page 35 and 36:
3.3 Korrektion af data 21 Figur 3.4
Page 37 and 38:
3.4 Resume af Kapitel 3 23 A(t) = A
Page 39 and 40:
Kapitel 4 Kantfindingsprogram I det
Page 41 and 42:
4.1 Programmets opbygning 27 Figur
Page 43 and 44:
Page 45 and 46:
4.1 Programmets opbygning 31 count
Page 47 and 48:
Page 49 and 50:
4.2 Resultater 35 Figur 4.10: Samme
Page 51 and 52:
4.3 Mavesækkens tømning 37 Figur
Page 53 and 54:
Page 55 and 56:
Page 57 and 58:
4.4 Resume af Kapitel 4 43 Figur 4.
Page 59 and 60:
Kapitel 5 Forsøg med normoglykæmi
Page 61 and 62:
5.1 Forsøgsprocedure 47 Figur 5.2:
Page 63 and 64:
5.3 7 modeller for mavesækkens tø
Page 65 and 66:
Page 67 and 68:
Page 69 and 70:
Page 71 and 72:
Page 73 and 74:
5.4 Sammenligning af de 7 modeller
Page 75 and 76:
5.5 Resume af Kapitel 5 61 5.5 Resu
Page 77 and 78:
Kapitel 6 Simulering af forsøgssce
Page 79 and 80:
6.1 Hovorka modellen 65 ˙Q1(t) = U
Page 81 and 82:
6.2 Implementering af model for bug
Page 83 and 84:
6.2 Implementering af model for bug
Page 85 and 86:
6.3 Simulering af clamp-forsøg 71
Page 87 and 88:
Page 89 and 90:
Page 91 and 92:
6.4 Diskussion af simulering af cla
Page 93 and 94:
6.5 Resume af Kapitel 6 79 ducerer
Page 95 and 96:
Kapitel 7 Konklusion I dette bachel
Page 97 and 98:
Bilag A MATLAB kode til kantfinding
Page 99 and 100:
79 xlabel('Time [min]','fontsize',1
Page 101 and 102: 22 if Data(i,j) ≥ cs 23 if Data(i
Page 103 and 104: Bilag B MATLAB kode til fit af data
Page 105 and 106: 82 t = 0:1:400; 83 Q = (1 + K*(t/te
Page 107 and 108: Bilag C MATLAB kode til behandling
Page 109 and 110: 79 % Plot of the model of Y with da
Page 111 and 112: 189 %%%%%%%%%%%%%%%%%%%%%%%%% 1 par
Page 113 and 114: 299 print('−dpng', '−loose', ['
Page 115 and 116: Bilag D MATLAB kode til simulering
Page 117 and 118: 13 % 14 % time : t [min] 103 15 % S
Page 119 and 120: 105 123 Q2dot = Q12 − Q21 − Q2o
Page 121 and 122: 41 % Modified 23.07.09 SW 107 42 %
Page 123 and 124: 109 81 subplot(223) 82 stairs(T,D,'
Page 125 and 126: 90 91 % Plot of iv insulin infusion
Page 127 and 128: 99 ylabel('Insulin infusion (mU/min
Page 129 and 130: Bilag E Billeder fra forsøg med no
Page 131 and 132: 117 Figur E.3: Her ses forsøgspers
Page 133 and 134: Bilag F Formelle dokumenter i forbi
Page 135 and 136: Komitéens reg.nr. (KF)____________
Page 138 and 139: Formål Formålet med dette projekt
Page 140 and 141: Forsøgsprocedure Efter forudgåend
Page 142 and 143: Publikation Forsøgsresultaterne vi
Page 144 and 145: Effekten af hypo-, normo- og hyperg
Page 146 and 147: Driftsomkostninger og udgifter til
Page 148 and 149: til at dosere indsprøjtningerne af
Page 150 and 151: Følgende annonce indrykkes på int
Page 154: 140 LITTERATUR [34] K. Vollmer, H.
show all

Matematisk Model for Mavesækkens Tømning - Danmarks Tekniske ...

Create successful ePaper yourself

Delete template?

Save as template?